Singlet Oxygen Toxicity Is Cell Line-dependent: A Study of Lipid Peroxidation in Nine Leukemia Cell Lines

Singlet oxygen (1O2) can be quenched by water, lipids, proteins, nucleic acids and other small molecules. Polyunsaturated fatty acids (PUFA) of cells principally quench 1O2 by chemical mechanisms, producing lipid hydroperoxides, while proteins physically and chemically quench 1O2. Because cell lines...

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Veröffentlicht in:	Photochemistry and photobiology 1999-12, Vol.70 (6), p.858-867
Hauptverfasser:	Schafer, Freya Q., Buettner, Garry R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals HL-60 Cells - drug effects HL-60 Cells - metabolism Humans K562 Cells - drug effects K562 Cells - metabolism Leukemia L1210 - drug therapy Leukemia L1210 - metabolism Leukemia, Experimental - drug therapy Leukemia, Experimental - metabolism Lipid Peroxidation - drug effects Mice Oxygen - toxicity Tumor Cells, Cultured
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