Regioselective synthesis and evaluation of novel sulfonamide 1,2,3-triazole derivatives as antitumor agents

A novel series of 1,2,3-triazole containing sulfonamide moiety was synthesized. Treatment of 4-acetyl 1,2,3-triazole 3 with different aldehydes gave α , β -unsaturated ketones 4a – c . Condensation of 3 with dimethylformamide dimethylacetal (DMF-DMA) gave formimidamide 5 . Chalcone 7 was achieved vi...

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