Development of film coated orally disintegrating tablets “REMITCH® OD TABLETS 2.5µg

The orally disintegrating tablets REMITCH® OD TABLETS 2.5µg composing Nalfurafine hydrochloride was launched. The composition rate of the active ingredient is extremely low and the Nalfurafine is unstable for temperature, humidity and light. To overcome these difficulties, the original film coating...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Drug Delivery System 2019/11/25, Vol.34(5), pp.390-393
Hauptverfasser:	Ohta, Kotoe, Takaki, Suguru, Minakami, Satoshi, Fujisaki, Yuki, Horiuchi, Yasuhide
Format:	Artikel
Sprache:	eng ; jpn
Schlagworte:	Disintegration film coating nalfurafine Orally disintegrating tablet REMITCH Tablets Technology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

container_end_page	393
container_issue	5
container_start_page	390
container_title	Drug Delivery System
container_volume	34
creator	Ohta, Kotoe Takaki, Suguru Minakami, Satoshi Fujisaki, Yuki Horiuchi, Yasuhide
description	The orally disintegrating tablets REMITCH® OD TABLETS 2.5µg composing Nalfurafine hydrochloride was launched. The composition rate of the active ingredient is extremely low and the Nalfurafine is unstable for temperature, humidity and light. To overcome these difficulties, the original film coating technology for OD tablets “RADIFIL®” was developed and applied to “REMITCH® OD TABLETS 2.5µg”. The key technology of RADIFIL® and the bioequivalence study between REMITCH® CAPSULES 2.5μg and REMITCH® OD TABLETS 2.5µg was summarized in this report.
doi_str_mv	10.2745/dds.34.390
format	Article
fullrecord	<record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_2369558604</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2369558604</sourcerecordid><originalsourceid>FETCH-LOGICAL-c1530-5b7ff8cef9eef40dee4f81cb70b972060b280b9d6a4ee3a9884ae860c7b3d7d63</originalsourceid><addsrcrecordid>eNo90M1KAzEQB_AgCtbqxScIeBN2zW6S_Th4qG3VQqWgFY8hm53ULdvdmqRCbz6Iz-DNF-ij-CRGWnuaYebHDPwROo9IGKeMX5WlDSkLaU4OUCfKsiiIUxofog7JIxpwQpJjdGLtnBDml1EHvQzgHep2uYDG4VZjXdULrFrpoMStkXW9xmVlq8bBzEhXNTPsZFGDs_jn4_Nx-DCa9u83X3gywNPezXg4fcJxyDffs1N0pGVt4WxXu-j5duhtMJ7cjfq9caAiTknAi1TrTIHOATQjJQDTWaSKlBR5GpOEFHHm2zKRDIDKPMuYhCwhKi1omZYJ7aKL7d2lad9WYJ2YtyvT-JcipknOucfMq8utUqa11oAWS1MtpFmLiIi_4IQPTlAmfHAeX2_x3Do5gz2VxlWqhn_Kd34_V6_SCGjoLxF_eEY</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2369558604</pqid></control><display><type>article</type><title>Development of film coated orally disintegrating tablets “REMITCH® OD TABLETS 2.5µg</title><source>J-STAGE Free</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><creator>Ohta, Kotoe ; Takaki, Suguru ; Minakami, Satoshi ; Fujisaki, Yuki ; Horiuchi, Yasuhide</creator><creatorcontrib>Ohta, Kotoe ; Takaki, Suguru ; Minakami, Satoshi ; Fujisaki, Yuki ; Horiuchi, Yasuhide</creatorcontrib><description>The orally disintegrating tablets REMITCH® OD TABLETS 2.5µg composing Nalfurafine hydrochloride was launched. The composition rate of the active ingredient is extremely low and the Nalfurafine is unstable for temperature, humidity and light. To overcome these difficulties, the original film coating technology for OD tablets “RADIFIL®” was developed and applied to “REMITCH® OD TABLETS 2.5µg”. The key technology of RADIFIL® and the bioequivalence study between REMITCH® CAPSULES 2.5μg and REMITCH® OD TABLETS 2.5µg was summarized in this report.</description><identifier>ISSN: 0913-5006</identifier><identifier>EISSN: 1881-2732</identifier><identifier>DOI: 10.2745/dds.34.390</identifier><language>eng ; jpn</language><publisher>Kawasaki: THE JAPAN SOCIETY OF DRUG DELIVERY SYSTEM</publisher><subject>Disintegration ; film coating ; nalfurafine ; Orally disintegrating tablet ; REMITCH ; Tablets ; Technology</subject><ispartof>Drug Delivery System, 2019/11/25, Vol.34(5), pp.390-393</ispartof><rights>2019 The Japan Society of Drug Delivery System</rights><rights>Copyright Japan Science and Technology Agency 2019</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c1530-5b7ff8cef9eef40dee4f81cb70b972060b280b9d6a4ee3a9884ae860c7b3d7d63</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,1877,27901,27902</link.rule.ids></links><search><creatorcontrib>Ohta, Kotoe</creatorcontrib><creatorcontrib>Takaki, Suguru</creatorcontrib><creatorcontrib>Minakami, Satoshi</creatorcontrib><creatorcontrib>Fujisaki, Yuki</creatorcontrib><creatorcontrib>Horiuchi, Yasuhide</creatorcontrib><title>Development of film coated orally disintegrating tablets “REMITCH® OD TABLETS 2.5µg</title><title>Drug Delivery System</title><addtitle>DDS</addtitle><description>The orally disintegrating tablets REMITCH® OD TABLETS 2.5µg composing Nalfurafine hydrochloride was launched. The composition rate of the active ingredient is extremely low and the Nalfurafine is unstable for temperature, humidity and light. To overcome these difficulties, the original film coating technology for OD tablets “RADIFIL®” was developed and applied to “REMITCH® OD TABLETS 2.5µg”. The key technology of RADIFIL® and the bioequivalence study between REMITCH® CAPSULES 2.5μg and REMITCH® OD TABLETS 2.5µg was summarized in this report.</description><subject>Disintegration</subject><subject>film coating</subject><subject>nalfurafine</subject><subject>Orally disintegrating tablet</subject><subject>REMITCH</subject><subject>Tablets</subject><subject>Technology</subject><issn>0913-5006</issn><issn>1881-2732</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><recordid>eNo90M1KAzEQB_AgCtbqxScIeBN2zW6S_Th4qG3VQqWgFY8hm53ULdvdmqRCbz6Iz-DNF-ij-CRGWnuaYebHDPwROo9IGKeMX5WlDSkLaU4OUCfKsiiIUxofog7JIxpwQpJjdGLtnBDml1EHvQzgHep2uYDG4VZjXdULrFrpoMStkXW9xmVlq8bBzEhXNTPsZFGDs_jn4_Nx-DCa9u83X3gywNPezXg4fcJxyDffs1N0pGVt4WxXu-j5duhtMJ7cjfq9caAiTknAi1TrTIHOATQjJQDTWaSKlBR5GpOEFHHm2zKRDIDKPMuYhCwhKi1omZYJ7aKL7d2lad9WYJ2YtyvT-JcipknOucfMq8utUqa11oAWS1MtpFmLiIi_4IQPTlAmfHAeX2_x3Do5gz2VxlWqhn_Kd34_V6_SCGjoLxF_eEY</recordid><startdate>20191125</startdate><enddate>20191125</enddate><creator>Ohta, Kotoe</creator><creator>Takaki, Suguru</creator><creator>Minakami, Satoshi</creator><creator>Fujisaki, Yuki</creator><creator>Horiuchi, Yasuhide</creator><general>THE JAPAN SOCIETY OF DRUG DELIVERY SYSTEM</general><general>Japan Science and Technology Agency</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope></search><sort><creationdate>20191125</creationdate><title>Development of film coated orally disintegrating tablets “REMITCH® OD TABLETS 2.5µg</title><author>Ohta, Kotoe ; Takaki, Suguru ; Minakami, Satoshi ; Fujisaki, Yuki ; Horiuchi, Yasuhide</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c1530-5b7ff8cef9eef40dee4f81cb70b972060b280b9d6a4ee3a9884ae860c7b3d7d63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng ; jpn</language><creationdate>2019</creationdate><topic>Disintegration</topic><topic>film coating</topic><topic>nalfurafine</topic><topic>Orally disintegrating tablet</topic><topic>REMITCH</topic><topic>Tablets</topic><topic>Technology</topic><toplevel>online_resources</toplevel><creatorcontrib>Ohta, Kotoe</creatorcontrib><creatorcontrib>Takaki, Suguru</creatorcontrib><creatorcontrib>Minakami, Satoshi</creatorcontrib><creatorcontrib>Fujisaki, Yuki</creatorcontrib><creatorcontrib>Horiuchi, Yasuhide</creatorcontrib><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>Drug Delivery System</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ohta, Kotoe</au><au>Takaki, Suguru</au><au>Minakami, Satoshi</au><au>Fujisaki, Yuki</au><au>Horiuchi, Yasuhide</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Development of film coated orally disintegrating tablets “REMITCH® OD TABLETS 2.5µg</atitle><jtitle>Drug Delivery System</jtitle><addtitle>DDS</addtitle><date>2019-11-25</date><risdate>2019</risdate><volume>34</volume><issue>5</issue><spage>390</spage><epage>393</epage><pages>390-393</pages><issn>0913-5006</issn><eissn>1881-2732</eissn><abstract>The orally disintegrating tablets REMITCH® OD TABLETS 2.5µg composing Nalfurafine hydrochloride was launched. The composition rate of the active ingredient is extremely low and the Nalfurafine is unstable for temperature, humidity and light. To overcome these difficulties, the original film coating technology for OD tablets “RADIFIL®” was developed and applied to “REMITCH® OD TABLETS 2.5µg”. The key technology of RADIFIL® and the bioequivalence study between REMITCH® CAPSULES 2.5μg and REMITCH® OD TABLETS 2.5µg was summarized in this report.</abstract><cop>Kawasaki</cop><pub>THE JAPAN SOCIETY OF DRUG DELIVERY SYSTEM</pub><doi>10.2745/dds.34.390</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record>
fulltext	fulltext
identifier	ISSN: 0913-5006
ispartof	Drug Delivery System, 2019/11/25, Vol.34(5), pp.390-393
issn	0913-5006 1881-2732
language	eng ; jpn
recordid	cdi_proquest_journals_2369558604
source	J-STAGE Free; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals
subjects	Disintegration film coating nalfurafine Orally disintegrating tablet REMITCH Tablets Technology
title	Development of film coated orally disintegrating tablets “REMITCH® OD TABLETS 2.5µg
url	https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-19T06%3A25%3A00IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Development%20of%20film%20coated%20orally%20disintegrating%20tablets%20%E2%80%9CREMITCH%C2%AE%20OD%20TABLETS%202.5%C2%B5g&rft.jtitle=Drug%20Delivery%20System&rft.au=Ohta,%20Kotoe&rft.date=2019-11-25&rft.volume=34&rft.issue=5&rft.spage=390&rft.epage=393&rft.pages=390-393&rft.issn=0913-5006&rft.eissn=1881-2732&rft_id=info:doi/10.2745/dds.34.390&rft_dat=%3Cproquest_cross%3E2369558604%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2369558604&rft_id=info:pmid/&rfr_iscdi=true