Glucuronidation as a metabolic barrier against zearalenone in rat everted intestine

Zearalenone (ZON), produced by Fusarium fungi, exhibits estrogenic activity. Livestock can be exposed to ZON orally through contaminating feeds such as cereals, leading to reproductive disorders such as infertility and miscarriage via endocrine system disruption. However, the details of ZON metaboli...

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Veröffentlicht in:	Journal of Veterinary Medical Science 2020, Vol.82(2), pp.153-161
Hauptverfasser:	IEKO, Takahiro, INOUE, Sumire, INOMATA, Yume, INOUE, Hiroki, FUJIKI, Jumpei, IWANO, Hidetomo
Format:	Artikel
Sprache:	eng
Schlagworte:	absorption Cereals Drug metabolism Endocrine disruptors Endocrine system Estrogenic activity everted intestine Fungi glucuronidation Infertility Intestine Life Sciences & Biomedicine Livestock Metabolism Metabolites Mucosa Science & Technology Toxicity Toxicology Veterinary Sciences Xenoestrogens Zearalenone
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