Determination of 1-Hydroxypyrene as a Biomarker for the Effects of Polycyclic Aromatic Hydrocarbons in Urine by Chromatography–Mass Spectrometry

A simple and sensitive procedure has been developed for the determination of 1-hydroxypyrene in urine as a biological marker of the effects of polycyclic aromatic hydrocarbons. After enzymatic hydrolysis for conjugate cleavage, the analyte was extracted from the matrix by liquid–liquid extraction wi...

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Veröffentlicht in:	Journal of analytical chemistry (New York, N.Y.) N.Y.), 2020, Vol.75 (1), p.84-89
Hauptverfasser:	Alekseenko, A. N., Zhurba, O. M., Merinov, A. V., Shayakhmetov, S. F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Analytical Chemistry Biomarkers Chemical tests and reagents Chemistry Chemistry and Materials Science Chromatography Enzymes Gas chromatography Hydrolysis Linearity Mass spectrometry Polycyclic aromatic hydrocarbons Reagents Room temperature
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