Activity and toxicity of 2-CDA in Langerhans cell histiocytosis: a single institutional experience

Langerhans cell histiocytosis (LCH) is a rare disorder characterized by clonal proliferation of immature and abnormal bone marrow derived langerhans cells. Treatment is usually multimodal. Potent anti-monocyte as well as immunomodulatory activity of 2-CDA and its proven efficacy in many lymphoprolif...

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Veröffentlicht in:	Indian journal of cancer 2007-10, Vol.44 (4), p.137
Hauptverfasser:	Biswas, G, Khadwal, A, Arora, B, Bhagwat, R, Banavali, S D, Nair, C N, Pai, S K, Kurkure, P A, Parikh, P M
Format:	Artikel
Sprache:	eng
Schlagworte:	2-Chloroadenosine - adverse effects 2-Chloroadenosine - analogs & derivatives 2-Chloroadenosine - immunology 2-Chloroadenosine - therapeutic use Antimetabolites, Antineoplastic - adverse effects Antimetabolites, Antineoplastic - immunology Antimetabolites, Antineoplastic - therapeutic use Antineoplastic Agents - adverse effects Antineoplastic Agents - immunology Antineoplastic Agents - therapeutic use Causes of Child, Preschool Cladribine Cladribine - adverse effects Cladribine - immunology Cladribine - therapeutic use Complications and side effects Deoxyadenosines - adverse effects Deoxyadenosines - immunology Deoxyadenosines - therapeutic use Diagnosis Dosage and administration Drug therapy Drug-Related Side Effects and Adverse Reactions Female Histiocytosis, Langerhans-Cell - drug therapy Histiocytosis, Langerhans-Cell - immunology Histiocytosis, Langerhans-Cell - physiopathology Humans Infant Langerhans-cell histiocytosis Male Medical examination Patients Pilot Projects Prospective Studies Time Factors
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