Biotechnological Potential of the Bacillus subtilis 20 Strain
— Bacillus subtilis bacteria play an important role in veterinary medicine, medicine, and biotechnology, and the permanently growing demand for biotechnological products fuels the improvement of the properties of biotechnological strains. B. subtilis strains with improved characteristics may be obta...
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| Veröffentlicht in: | Molecular biology (New York) 2020, Vol.54 (1), p.119-127 |
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| creator | Karpov, D. S. Domashin, A. I. Kotlov, M. I. Osipova, P. G. Kiseleva, S. V. Seregina, T. A. Goncharenko, A. V. Mironov, A. S. Karpov, V. L. Poddubko, S. V. |
| description | —
Bacillus subtilis
bacteria play an important role in veterinary medicine, medicine, and biotechnology, and the permanently growing demand for biotechnological products fuels the improvement of the properties of biotechnological strains.
B. subtilis
strains with improved characteristics may be obtained by rational design and the directed evolution technologies, or be found among newly described strains. In the course of the long-term microbiome composition studies in the Russian segment of the International Space Station, the
B. subtilis
20 strain was isolated, this strain shows the capacity for rapid growth and considerable biomass accumulation, as well as increased resistance to acidification of the environment in comparison to the “terrestrial”
B. subtilis
168 strain. What is more,
B. subtilis
20 is hyperresistant to the DNA and protein damaging factors that are linked to the overexpression of the genes controlling DNA repair, hydrogen sulfide production, and reactive oxygen species neutralization. The described properties of
B. subtilis
20 are indicative of its considerable potential as a promising producer of biologically active compounds. |
| doi_str_mv | 10.1134/S0026893320010082 |
| format | Article |
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Bacillus subtilis
bacteria play an important role in veterinary medicine, medicine, and biotechnology, and the permanently growing demand for biotechnological products fuels the improvement of the properties of biotechnological strains.
B. subtilis
strains with improved characteristics may be obtained by rational design and the directed evolution technologies, or be found among newly described strains. In the course of the long-term microbiome composition studies in the Russian segment of the International Space Station, the
B. subtilis
20 strain was isolated, this strain shows the capacity for rapid growth and considerable biomass accumulation, as well as increased resistance to acidification of the environment in comparison to the “terrestrial”
B. subtilis
168 strain. What is more,
B. subtilis
20 is hyperresistant to the DNA and protein damaging factors that are linked to the overexpression of the genes controlling DNA repair, hydrogen sulfide production, and reactive oxygen species neutralization. The described properties of
B. subtilis
20 are indicative of its considerable potential as a promising producer of biologically active compounds.</description><identifier>ISSN: 0026-8933</identifier><identifier>EISSN: 1608-3245</identifier><identifier>DOI: 10.1134/S0026893320010082</identifier><language>eng</language><publisher>Moscow: Pleiades Publishing</publisher><subject>Acidification ; Bacillus subtilis ; Bioactive compounds ; Biochemistry ; Biological activity ; Biomedical and Life Sciences ; Biotechnology ; Deoxyribonucleic acid ; Directed evolution ; DNA ; DNA damage ; DNA repair ; Human Genetics ; Hydrogen sulfide ; Life Sciences ; Microbiomes ; Molecular Cell Biology ; Oxidative stress ; Reactive oxygen species ; Strains (organisms) ; Veterinary medicine</subject><ispartof>Molecular biology (New York), 2020, Vol.54 (1), p.119-127</ispartof><rights>Pleiades Publishing, Inc. 2020</rights><rights>2020© Pleiades Publishing, Inc. 2020</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c246t-82629613a64055d265b26b2471e7a4fe44bf2fa090f334dafb64837a5a76493</citedby><cites>FETCH-LOGICAL-c246t-82629613a64055d265b26b2471e7a4fe44bf2fa090f334dafb64837a5a76493</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1134/S0026893320010082$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1134/S0026893320010082$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids></links><search><creatorcontrib>Karpov, D. S.</creatorcontrib><creatorcontrib>Domashin, A. I.</creatorcontrib><creatorcontrib>Kotlov, M. I.</creatorcontrib><creatorcontrib>Osipova, P. G.</creatorcontrib><creatorcontrib>Kiseleva, S. V.</creatorcontrib><creatorcontrib>Seregina, T. A.</creatorcontrib><creatorcontrib>Goncharenko, A. V.</creatorcontrib><creatorcontrib>Mironov, A. S.</creatorcontrib><creatorcontrib>Karpov, V. L.</creatorcontrib><creatorcontrib>Poddubko, S. V.</creatorcontrib><title>Biotechnological Potential of the Bacillus subtilis 20 Strain</title><title>Molecular biology (New York)</title><addtitle>Mol Biol</addtitle><description>—
Bacillus subtilis
bacteria play an important role in veterinary medicine, medicine, and biotechnology, and the permanently growing demand for biotechnological products fuels the improvement of the properties of biotechnological strains.
B. subtilis
strains with improved characteristics may be obtained by rational design and the directed evolution technologies, or be found among newly described strains. In the course of the long-term microbiome composition studies in the Russian segment of the International Space Station, the
B. subtilis
20 strain was isolated, this strain shows the capacity for rapid growth and considerable biomass accumulation, as well as increased resistance to acidification of the environment in comparison to the “terrestrial”
B. subtilis
168 strain. What is more,
B. subtilis
20 is hyperresistant to the DNA and protein damaging factors that are linked to the overexpression of the genes controlling DNA repair, hydrogen sulfide production, and reactive oxygen species neutralization. The described properties of
B. subtilis
20 are indicative of its considerable potential as a promising producer of biologically active compounds.</description><subject>Acidification</subject><subject>Bacillus subtilis</subject><subject>Bioactive compounds</subject><subject>Biochemistry</subject><subject>Biological activity</subject><subject>Biomedical and Life Sciences</subject><subject>Biotechnology</subject><subject>Deoxyribonucleic acid</subject><subject>Directed evolution</subject><subject>DNA</subject><subject>DNA damage</subject><subject>DNA repair</subject><subject>Human Genetics</subject><subject>Hydrogen sulfide</subject><subject>Life Sciences</subject><subject>Microbiomes</subject><subject>Molecular Cell Biology</subject><subject>Oxidative stress</subject><subject>Reactive oxygen species</subject><subject>Strains (organisms)</subject><subject>Veterinary medicine</subject><issn>0026-8933</issn><issn>1608-3245</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNp1kE9PwzAMxSMEEmPwAbhV4lxwHDdtDxzYxD9pEkjjXqVdsmUqzUjSA9-ejCFxQJxs6_2eLT_GLjlccy7oZgmAsqqFQAAOUOERm3AJVS6QimM22cv5Xj9lZyFsvyGOE3Y7sy7qbjO43q1tp_rsNc1DtKlzJosbnc1UZ_t-DFkY22h7GzKEbBm9ssM5OzGqD_rip07Z8uH-bf6UL14en-d3i7xDkjGvUGItuVCSoChWKIsWZYtUcl0qMpqoNWgU1GCEoJUyraRKlKpQpaRaTNnVYevOu49Rh9hs3eiHdLBBIYkTpB8TxQ9U510IXptm5-278p8Nh2afUfMno-TBgyckdlhr_7v5f9MX-BBl7Q</recordid><startdate>2020</startdate><enddate>2020</enddate><creator>Karpov, D. S.</creator><creator>Domashin, A. I.</creator><creator>Kotlov, M. I.</creator><creator>Osipova, P. G.</creator><creator>Kiseleva, S. V.</creator><creator>Seregina, T. A.</creator><creator>Goncharenko, A. V.</creator><creator>Mironov, A. S.</creator><creator>Karpov, V. L.</creator><creator>Poddubko, S. V.</creator><general>Pleiades Publishing</general><general>Springer Nature B.V</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>7QR</scope><scope>7T5</scope><scope>7TK</scope><scope>7TM</scope><scope>7TO</scope><scope>7U9</scope><scope>8FD</scope><scope>FR3</scope><scope>H94</scope><scope>K9.</scope><scope>P64</scope><scope>RC3</scope></search><sort><creationdate>2020</creationdate><title>Biotechnological Potential of the Bacillus subtilis 20 Strain</title><author>Karpov, D. S. ; Domashin, A. I. ; Kotlov, M. I. ; Osipova, P. G. ; Kiseleva, S. V. ; Seregina, T. A. ; Goncharenko, A. V. ; Mironov, A. S. ; Karpov, V. L. ; Poddubko, S. V.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c246t-82629613a64055d265b26b2471e7a4fe44bf2fa090f334dafb64837a5a76493</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Acidification</topic><topic>Bacillus subtilis</topic><topic>Bioactive compounds</topic><topic>Biochemistry</topic><topic>Biological activity</topic><topic>Biomedical and Life Sciences</topic><topic>Biotechnology</topic><topic>Deoxyribonucleic acid</topic><topic>Directed evolution</topic><topic>DNA</topic><topic>DNA damage</topic><topic>DNA repair</topic><topic>Human Genetics</topic><topic>Hydrogen sulfide</topic><topic>Life Sciences</topic><topic>Microbiomes</topic><topic>Molecular Cell Biology</topic><topic>Oxidative stress</topic><topic>Reactive oxygen species</topic><topic>Strains (organisms)</topic><topic>Veterinary medicine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Karpov, D. S.</creatorcontrib><creatorcontrib>Domashin, A. I.</creatorcontrib><creatorcontrib>Kotlov, M. I.</creatorcontrib><creatorcontrib>Osipova, P. G.</creatorcontrib><creatorcontrib>Kiseleva, S. V.</creatorcontrib><creatorcontrib>Seregina, T. A.</creatorcontrib><creatorcontrib>Goncharenko, A. V.</creatorcontrib><creatorcontrib>Mironov, A. S.</creatorcontrib><creatorcontrib>Karpov, V. L.</creatorcontrib><creatorcontrib>Poddubko, S. V.</creatorcontrib><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><jtitle>Molecular biology (New York)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Karpov, D. S.</au><au>Domashin, A. I.</au><au>Kotlov, M. I.</au><au>Osipova, P. G.</au><au>Kiseleva, S. V.</au><au>Seregina, T. A.</au><au>Goncharenko, A. V.</au><au>Mironov, A. S.</au><au>Karpov, V. L.</au><au>Poddubko, S. V.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Biotechnological Potential of the Bacillus subtilis 20 Strain</atitle><jtitle>Molecular biology (New York)</jtitle><stitle>Mol Biol</stitle><date>2020</date><risdate>2020</risdate><volume>54</volume><issue>1</issue><spage>119</spage><epage>127</epage><pages>119-127</pages><issn>0026-8933</issn><eissn>1608-3245</eissn><abstract>—
Bacillus subtilis
bacteria play an important role in veterinary medicine, medicine, and biotechnology, and the permanently growing demand for biotechnological products fuels the improvement of the properties of biotechnological strains.
B. subtilis
strains with improved characteristics may be obtained by rational design and the directed evolution technologies, or be found among newly described strains. In the course of the long-term microbiome composition studies in the Russian segment of the International Space Station, the
B. subtilis
20 strain was isolated, this strain shows the capacity for rapid growth and considerable biomass accumulation, as well as increased resistance to acidification of the environment in comparison to the “terrestrial”
B. subtilis
168 strain. What is more,
B. subtilis
20 is hyperresistant to the DNA and protein damaging factors that are linked to the overexpression of the genes controlling DNA repair, hydrogen sulfide production, and reactive oxygen species neutralization. The described properties of
B. subtilis
20 are indicative of its considerable potential as a promising producer of biologically active compounds.</abstract><cop>Moscow</cop><pub>Pleiades Publishing</pub><doi>10.1134/S0026893320010082</doi><tpages>9</tpages></addata></record> |
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| identifier | ISSN: 0026-8933 |
| ispartof | Molecular biology (New York), 2020, Vol.54 (1), p.119-127 |
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| source | Springer Nature - Complete Springer Journals |
| subjects | Acidification Bacillus subtilis Bioactive compounds Biochemistry Biological activity Biomedical and Life Sciences Biotechnology Deoxyribonucleic acid Directed evolution DNA DNA damage DNA repair Human Genetics Hydrogen sulfide Life Sciences Microbiomes Molecular Cell Biology Oxidative stress Reactive oxygen species Strains (organisms) Veterinary medicine |
| title | Biotechnological Potential of the Bacillus subtilis 20 Strain |
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