Clinician Feedback- and Laboratory Auditing-Based Addition of Glucuronide Metabolites to a Multiplex Urine UPLC-MS/MS Assay for Use in Chronic Pain Management

Abstract Background We previously described the clinical validation of a second-generation rapid dilute-and-shoot ultra-performance liquid chromatography–tandem mass spectrometry (UPLC-MS/MS) assay to quantify and semi-quantify over 30 prescription drugs, drugs of abuse, and related glucuronides and...

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Veröffentlicht in:	American journal of clinical pathology 2018-09, Vol.150 (suppl_1), p.S159-S160
Hauptverfasser:	Dahlin, Jayme L, Gencheva, Ralitsa, Kantartjis, Michalis, Melanson, Stacy E F, Petrides, Athena
Format:	Artikel
Sprache:	eng
Schlagworte:	Chronic pain Clinical decision making Decision making Diazepam Drug abuse Drug metabolism Feedback Hydrolysis Ionization Ions Liquid chromatography Lorazepam Mass spectroscopy Metabolites Pain management Purification Urine
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