Carbohydrate to Itaconic Acid Conversion by Aspergillus terreus and the Evaluation of Process Monitoring Based on the Measurement of CO2
In this work, itaconic acid (IA) was produced biotechnologically by Aspergillus terreus fungal strain from glucose. The performance of the batch fermentation was kinetically assessed and the maximal IA production potential, maximal production rate and lag-phase time were determined as 28.1 g/L, 3.83...
Gespeichert in:
| Veröffentlicht in: | Waste and biomass valorization 2020-03, Vol.11 (3), p.1069-1075 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1075 |
|---|---|
| container_issue | 3 |
| container_start_page | 1069 |
| container_title | Waste and biomass valorization |
| container_volume | 11 |
| creator | Nemestóthy, Nándor Komáromy, Péter Bakonyi, Péter Tóth, András Levente Tóth, Gábor Gubicza, László Bélafi-Bakó, Katalin |
| description | In this work, itaconic acid (IA) was produced biotechnologically by
Aspergillus terreus
fungal strain from glucose. The performance of the batch fermentation was kinetically assessed and the maximal IA production potential, maximal production rate and lag-phase time were determined as 28.1 g/L, 3.83 g/L day and 1.52 days, respectively. In addition, the bioprocess was evaluated based on the most frequently used parameters, in particular IA titer (26.3 g/L), yield (0.22 g/g substrate) and productivity (0.1 g/L h), which were comparable to the already published literature. Furthermore, an on-line monitoring system was installed to the fermenter in order to measure the CO
2
content of the bioreactor off-gas. Actually, it was indicated by the results that the CO
2
production could have a linear-like relationship with the quantity of fungal biomass. Hence, the data collected in such a way may have the potential to establish an alternative methodology for the monitoring of biomass growth in the course of the biological transformation taking place.
Graphic Abstract |
| doi_str_mv | 10.1007/s12649-019-00729-3 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_2361084434</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2361084434</sourcerecordid><originalsourceid>FETCH-LOGICAL-c400t-223b9bb63b98531e809dff110a4e51c5bd072d8da58c533a20d4ade44e954d83</originalsourceid><addsrcrecordid>eNp9kL1OwzAYRS0EEhX0BZgsMQf8l7-xRAUqtSpDBzbLib-0qdK42E6lvgGPjUMQbAz2Z8nnXssHoTtKHigh6aOjLBF5RGhYJGV5xC_QhGZpGrEkfr_8PQt6jabO7QkhjNKM8XSCPgtlS7M7a6s8YG_wwqvKdE2FZ1WjcWG6E1jXmA6XZzxzR7Dbpm17hz1YC2GqTmO_Azw_qbZXfiBNjd-sqcA5vApV3tim2-In5UDjcD3QK1Cut3CAzg94sWa36KpWrYPpz7xBm-f5pniNluuXRTFbRpUgxEeM8TIvyyTsWcwpZCTXdU0pUQJiWsWlDgZ0plWcVTHnihEtlAYhII-FzvgNuh9rj9Z89OC83JveduFFyXhCSSYEF4FiI1VZ45yFWh5tc1D2LCmRg3M5OpfBufx2LnkI8THkjsOHwf5V_5P6AvdkhYY</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2361084434</pqid></control><display><type>article</type><title>Carbohydrate to Itaconic Acid Conversion by Aspergillus terreus and the Evaluation of Process Monitoring Based on the Measurement of CO2</title><source>Springer Nature - Complete Springer Journals</source><creator>Nemestóthy, Nándor ; Komáromy, Péter ; Bakonyi, Péter ; Tóth, András Levente ; Tóth, Gábor ; Gubicza, László ; Bélafi-Bakó, Katalin</creator><creatorcontrib>Nemestóthy, Nándor ; Komáromy, Péter ; Bakonyi, Péter ; Tóth, András Levente ; Tóth, Gábor ; Gubicza, László ; Bélafi-Bakó, Katalin</creatorcontrib><description>In this work, itaconic acid (IA) was produced biotechnologically by
Aspergillus terreus
fungal strain from glucose. The performance of the batch fermentation was kinetically assessed and the maximal IA production potential, maximal production rate and lag-phase time were determined as 28.1 g/L, 3.83 g/L day and 1.52 days, respectively. In addition, the bioprocess was evaluated based on the most frequently used parameters, in particular IA titer (26.3 g/L), yield (0.22 g/g substrate) and productivity (0.1 g/L h), which were comparable to the already published literature. Furthermore, an on-line monitoring system was installed to the fermenter in order to measure the CO
2
content of the bioreactor off-gas. Actually, it was indicated by the results that the CO
2
production could have a linear-like relationship with the quantity of fungal biomass. Hence, the data collected in such a way may have the potential to establish an alternative methodology for the monitoring of biomass growth in the course of the biological transformation taking place.
Graphic Abstract</description><identifier>ISSN: 1877-2641</identifier><identifier>EISSN: 1877-265X</identifier><identifier>DOI: 10.1007/s12649-019-00729-3</identifier><language>eng</language><publisher>Dordrecht: Springer Netherlands</publisher><subject>Aspergillus terreus ; Biomass ; Bioreactors ; Carbohydrates ; Carbon dioxide ; Engineering ; Environment ; Environmental Engineering/Biotechnology ; Fermentation ; Fungi ; Industrial Pollution Prevention ; Itaconic acid ; Monitoring ; On-line systems ; Original Paper ; Renewable and Green Energy ; Substrates ; Waste Management/Waste Technology</subject><ispartof>Waste and biomass valorization, 2020-03, Vol.11 (3), p.1069-1075</ispartof><rights>The Author(s) 2019</rights><rights>This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c400t-223b9bb63b98531e809dff110a4e51c5bd072d8da58c533a20d4ade44e954d83</citedby><cites>FETCH-LOGICAL-c400t-223b9bb63b98531e809dff110a4e51c5bd072d8da58c533a20d4ade44e954d83</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s12649-019-00729-3$$EPDF$$P50$$Gspringer$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s12649-019-00729-3$$EHTML$$P50$$Gspringer$$Hfree_for_read</linktohtml><link.rule.ids>314,776,780,27903,27904,41467,42536,51297</link.rule.ids></links><search><creatorcontrib>Nemestóthy, Nándor</creatorcontrib><creatorcontrib>Komáromy, Péter</creatorcontrib><creatorcontrib>Bakonyi, Péter</creatorcontrib><creatorcontrib>Tóth, András Levente</creatorcontrib><creatorcontrib>Tóth, Gábor</creatorcontrib><creatorcontrib>Gubicza, László</creatorcontrib><creatorcontrib>Bélafi-Bakó, Katalin</creatorcontrib><title>Carbohydrate to Itaconic Acid Conversion by Aspergillus terreus and the Evaluation of Process Monitoring Based on the Measurement of CO2</title><title>Waste and biomass valorization</title><addtitle>Waste Biomass Valor</addtitle><description>In this work, itaconic acid (IA) was produced biotechnologically by
Aspergillus terreus
fungal strain from glucose. The performance of the batch fermentation was kinetically assessed and the maximal IA production potential, maximal production rate and lag-phase time were determined as 28.1 g/L, 3.83 g/L day and 1.52 days, respectively. In addition, the bioprocess was evaluated based on the most frequently used parameters, in particular IA titer (26.3 g/L), yield (0.22 g/g substrate) and productivity (0.1 g/L h), which were comparable to the already published literature. Furthermore, an on-line monitoring system was installed to the fermenter in order to measure the CO
2
content of the bioreactor off-gas. Actually, it was indicated by the results that the CO
2
production could have a linear-like relationship with the quantity of fungal biomass. Hence, the data collected in such a way may have the potential to establish an alternative methodology for the monitoring of biomass growth in the course of the biological transformation taking place.
Graphic Abstract</description><subject>Aspergillus terreus</subject><subject>Biomass</subject><subject>Bioreactors</subject><subject>Carbohydrates</subject><subject>Carbon dioxide</subject><subject>Engineering</subject><subject>Environment</subject><subject>Environmental Engineering/Biotechnology</subject><subject>Fermentation</subject><subject>Fungi</subject><subject>Industrial Pollution Prevention</subject><subject>Itaconic acid</subject><subject>Monitoring</subject><subject>On-line systems</subject><subject>Original Paper</subject><subject>Renewable and Green Energy</subject><subject>Substrates</subject><subject>Waste Management/Waste Technology</subject><issn>1877-2641</issn><issn>1877-265X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><recordid>eNp9kL1OwzAYRS0EEhX0BZgsMQf8l7-xRAUqtSpDBzbLib-0qdK42E6lvgGPjUMQbAz2Z8nnXssHoTtKHigh6aOjLBF5RGhYJGV5xC_QhGZpGrEkfr_8PQt6jabO7QkhjNKM8XSCPgtlS7M7a6s8YG_wwqvKdE2FZ1WjcWG6E1jXmA6XZzxzR7Dbpm17hz1YC2GqTmO_Azw_qbZXfiBNjd-sqcA5vApV3tim2-In5UDjcD3QK1Cut3CAzg94sWa36KpWrYPpz7xBm-f5pniNluuXRTFbRpUgxEeM8TIvyyTsWcwpZCTXdU0pUQJiWsWlDgZ0plWcVTHnihEtlAYhII-FzvgNuh9rj9Z89OC83JveduFFyXhCSSYEF4FiI1VZ45yFWh5tc1D2LCmRg3M5OpfBufx2LnkI8THkjsOHwf5V_5P6AvdkhYY</recordid><startdate>20200301</startdate><enddate>20200301</enddate><creator>Nemestóthy, Nándor</creator><creator>Komáromy, Péter</creator><creator>Bakonyi, Péter</creator><creator>Tóth, András Levente</creator><creator>Tóth, Gábor</creator><creator>Gubicza, László</creator><creator>Bélafi-Bakó, Katalin</creator><general>Springer Netherlands</general><general>Springer Nature B.V</general><scope>C6C</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20200301</creationdate><title>Carbohydrate to Itaconic Acid Conversion by Aspergillus terreus and the Evaluation of Process Monitoring Based on the Measurement of CO2</title><author>Nemestóthy, Nándor ; Komáromy, Péter ; Bakonyi, Péter ; Tóth, András Levente ; Tóth, Gábor ; Gubicza, László ; Bélafi-Bakó, Katalin</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c400t-223b9bb63b98531e809dff110a4e51c5bd072d8da58c533a20d4ade44e954d83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Aspergillus terreus</topic><topic>Biomass</topic><topic>Bioreactors</topic><topic>Carbohydrates</topic><topic>Carbon dioxide</topic><topic>Engineering</topic><topic>Environment</topic><topic>Environmental Engineering/Biotechnology</topic><topic>Fermentation</topic><topic>Fungi</topic><topic>Industrial Pollution Prevention</topic><topic>Itaconic acid</topic><topic>Monitoring</topic><topic>On-line systems</topic><topic>Original Paper</topic><topic>Renewable and Green Energy</topic><topic>Substrates</topic><topic>Waste Management/Waste Technology</topic><toplevel>online_resources</toplevel><creatorcontrib>Nemestóthy, Nándor</creatorcontrib><creatorcontrib>Komáromy, Péter</creatorcontrib><creatorcontrib>Bakonyi, Péter</creatorcontrib><creatorcontrib>Tóth, András Levente</creatorcontrib><creatorcontrib>Tóth, Gábor</creatorcontrib><creatorcontrib>Gubicza, László</creatorcontrib><creatorcontrib>Bélafi-Bakó, Katalin</creatorcontrib><collection>Springer Nature OA Free Journals</collection><collection>CrossRef</collection><jtitle>Waste and biomass valorization</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nemestóthy, Nándor</au><au>Komáromy, Péter</au><au>Bakonyi, Péter</au><au>Tóth, András Levente</au><au>Tóth, Gábor</au><au>Gubicza, László</au><au>Bélafi-Bakó, Katalin</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Carbohydrate to Itaconic Acid Conversion by Aspergillus terreus and the Evaluation of Process Monitoring Based on the Measurement of CO2</atitle><jtitle>Waste and biomass valorization</jtitle><stitle>Waste Biomass Valor</stitle><date>2020-03-01</date><risdate>2020</risdate><volume>11</volume><issue>3</issue><spage>1069</spage><epage>1075</epage><pages>1069-1075</pages><issn>1877-2641</issn><eissn>1877-265X</eissn><abstract>In this work, itaconic acid (IA) was produced biotechnologically by
Aspergillus terreus
fungal strain from glucose. The performance of the batch fermentation was kinetically assessed and the maximal IA production potential, maximal production rate and lag-phase time were determined as 28.1 g/L, 3.83 g/L day and 1.52 days, respectively. In addition, the bioprocess was evaluated based on the most frequently used parameters, in particular IA titer (26.3 g/L), yield (0.22 g/g substrate) and productivity (0.1 g/L h), which were comparable to the already published literature. Furthermore, an on-line monitoring system was installed to the fermenter in order to measure the CO
2
content of the bioreactor off-gas. Actually, it was indicated by the results that the CO
2
production could have a linear-like relationship with the quantity of fungal biomass. Hence, the data collected in such a way may have the potential to establish an alternative methodology for the monitoring of biomass growth in the course of the biological transformation taking place.
Graphic Abstract</abstract><cop>Dordrecht</cop><pub>Springer Netherlands</pub><doi>10.1007/s12649-019-00729-3</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1877-2641 |
| ispartof | Waste and biomass valorization, 2020-03, Vol.11 (3), p.1069-1075 |
| issn | 1877-2641 1877-265X |
| language | eng |
| recordid | cdi_proquest_journals_2361084434 |
| source | Springer Nature - Complete Springer Journals |
| subjects | Aspergillus terreus Biomass Bioreactors Carbohydrates Carbon dioxide Engineering Environment Environmental Engineering/Biotechnology Fermentation Fungi Industrial Pollution Prevention Itaconic acid Monitoring On-line systems Original Paper Renewable and Green Energy Substrates Waste Management/Waste Technology |
| title | Carbohydrate to Itaconic Acid Conversion by Aspergillus terreus and the Evaluation of Process Monitoring Based on the Measurement of CO2 |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-24T01%3A45%3A21IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Carbohydrate%20to%20Itaconic%20Acid%20Conversion%20by%20Aspergillus%20terreus%20and%20the%20Evaluation%20of%20Process%20Monitoring%20Based%20on%20the%20Measurement%20of%20CO2&rft.jtitle=Waste%20and%20biomass%20valorization&rft.au=Nemest%C3%B3thy,%20N%C3%A1ndor&rft.date=2020-03-01&rft.volume=11&rft.issue=3&rft.spage=1069&rft.epage=1075&rft.pages=1069-1075&rft.issn=1877-2641&rft.eissn=1877-265X&rft_id=info:doi/10.1007/s12649-019-00729-3&rft_dat=%3Cproquest_cross%3E2361084434%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2361084434&rft_id=info:pmid/&rfr_iscdi=true |