The Influence of Food on the Bioavailability of a Twice-Daily Controlled Release Carbamazepine Formulation

Carbatrol®, a new dosage form of carbamazepine (CBZ), was developed consisting of three different types of pellets (immediate release, controlled release, and enteric release). The objective of this study was to explore the influence of food on absorption of CBZ. This was a randomized, open‐label, s...

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Veröffentlicht in:	Journal of clinical pharmacology 2001-02, Vol.41 (2), p.183-186
Hauptverfasser:	McLean, Angus, Browne, Susan, Zhang, Yuxin, Slaughter, Elizabeth, Halstenson, Charles, Couch, Richard
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Anticonvulsants - administration & dosage Anticonvulsants - chemistry Anticonvulsants - pharmacokinetics Anticonvulsants. Antiepileptics. Antiparkinson agents Area Under Curve Biological and medical sciences Biological Availability Carbamazepine - administration & dosage Carbamazepine - chemistry Carbamazepine - pharmacokinetics Chemistry, Pharmaceutical Cross-Over Studies Delayed-Action Preparations Food Food-Drug Interactions Humans Male Medical sciences Middle Aged Neuropharmacology Pharmacology. Drug treatments
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