Sequential Increases in Proliferating Cell Nuclear Antigen Expression in Head and Neck Tumorigenesis: A Potential Biomarker

Background: Proliferating cell nuclear antigen (PCNA) is a 36-kd nuclear protein whose expression is associated with DNA synthesis and cell proliferation. Tumorigenesis in head and neck squamous cell carcinoma is proposed to be a multistep process; dysregulation of proliferation is a potential marke...

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Veröffentlicht in:	JNCI : Journal of the National Cancer Institute 1993-06, Vol.85 (12), p.971-978
Hauptverfasser:	Shin, Dong M., Voravud, Narin, Ro, Jae Y., Lee, Jin S., Hong, Waun K., Hittelman, Walter N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, Neoplasm - analysis Biological and medical sciences Biomarkers, Tumor Cancer Carcinoma, Squamous Cell - immunology Carcinoma, Squamous Cell - pathology Head and Neck Neoplasms - immunology Head and Neck Neoplasms - pathology Humans Immunohistochemistry Medical research Medical sciences Neoplasm Staging Nuclear Proteins - analysis Otorhinolaryngology (head neck, general aspects and miscellaneous) Otorhinolaryngology. Stomatology Proliferating Cell Nuclear Antigen Proteins Tumors
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