Pharmacokinetics and Biodistribution of Rhopalurus junceus Scorpion Venom in Tumor-Bearing Mice after Intravenous and Oral Administration

Rhopalurus junceus scorpion venom has shown potential for anticancer treatment. However, there are no scientific evidence about venom pharmacokinetic (PK) and biodistribution (BD) in tumor-bearing mice. 131I-labeled venom was administrated by intravenous (IV) and oral (PO) routes at the single dose...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Iranian biomedical journal 2019-07, Vol.23 (4), p.287-296
Hauptverfasser:	Díaz-García, Alexis, Pimentel González, Gilmara, Basaco Bernabeu, Tais, Rodríguez Aurrecochea, Juan C., Rodríguez Sánchez, Hermis, Sánchez Monzón, Iraida, Hernández Gómez, Maikel, Rodríguez Torres, Caridad, Regla Rodríguez Capote, Maria, Guevara Orellanes, Irania
Format:	Artikel
Sprache:	eng
Schlagworte:	Bioavailability Intravenous administration Kidneys Lungs Oral administration Organs Pharmacokinetics Pharmacology Radioactivity Rhopalurus junceus Spleen Stomach Tumors Venom
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!