Identification of Two Novel Mutations in KDM3A Regulatory Gene in Iranian Infertile Males

Background: KDM3A is a key epigenetic regulator that is expressed in the testis and is required for packaging and condensation of sperm chromatin. To this point, the association of the KDM3A gene and infertility has not been studied in human. The aim of this study was to screen any new mutation in K...

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Veröffentlicht in:	Iranian biomedical journal 2019-05, Vol.23 (3), p.220-227
Hauptverfasser:	Hojati, Zohreh, Soleimanpour, Elaheh, Javadirad, Seyed-Morteza, Nasr-Esfahani, Mohammad Hossein
Format:	Artikel
Sprache:	eng
Schlagworte:	Abnormalities Chromatin Chromosome deletion Chromosomes Exons Gene deletion Infertility Lysine Males Men Molecular conformation Mutation Nucleotides Oligozoospermia Packaging Point mutation Polymerase chain reaction Polymorphism Sequence analysis Transversion mutation
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