Dominance of Variant Human Herpesvirus 6 A Among Hemodialysis Patients, Ahvaz, Iran
Introduction. Hemodialysis (HD) patients are a high-risk population for acquiring blood-borne viruses such as HHV-6. HHV-6 can remain latent in the host cells after primary infection; the reactivation of virus may result complications such as seizure, respiratory failure, hepatitis, and encephalitis...
Gespeichert in:
| Veröffentlicht in: | Iranian journal of kidney diseases 2019-11, Vol.13 (6), p.404 |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | 6 |
| container_start_page | 404 |
| container_title | Iranian journal of kidney diseases |
| container_volume | 13 |
| creator | Mahmoudvand, Shahab Shokri, Somayeh Nahid-Samiei, Rahil Gholam-Abbas Kaydani Makvandi, Manoochehr Jalilian, Shahram Shahbazian, Heshmatollah Shayanpour, Shokouh Kimia Makvandi Pirmoradi, Roya |
| description | Introduction. Hemodialysis (HD) patients are a high-risk population for acquiring blood-borne viruses such as HHV-6. HHV-6 can remain latent in the host cells after primary infection; the reactivation of virus may result complications such as seizure, respiratory failure, hepatitis, and encephalitis. There is a limited report concerning HHV-6 infection in HD patients in Iran. Thus, this study was conducted to determine the frequency of HHV-6 among HD patients.Methods. We determined HHV-6 DNA in sera samples of 84 patients undergoing HD. The DNA was extracted from the sera samples and the presence of HHV-6 DNA variants A and B was evaluated by nested PCR.Results. 52/84 (61.9%) of HD patients were males and 32/84 (38.1%) females. The age ranges of patients were between 18 to 85 years and the mean age was 52 ± 1.52 (± SD) years. Out of 84 sera samples, HHV-6 DNA was detected in 10 (11.9%) participants, including 6/52 (11.5%) in males and 4/32 (12.5%) in females. HHV- 6A was detected in 10/10 (100%) of positive cases. No HHV-6 B was found in HD patients. The distribution of HHV-6A DNA was not significant between genders (P > .05). Out of 84 HD patients, 55 (65.47%) cases were over 50 years, among them 10 (18.18%) cases were positive for HHV-6 A infection (P < .05).Conclusion. The results showed that only HHV-6 DNA variant A was found in 11.9% of HD patients. Regarding the consequence of HHV-6 reactivation, to manage and improve treatment, the screening of HHV-6 DNA test should be implemented for HD patients. |
| format | Article |
| fullrecord | <record><control><sourceid>proquest</sourceid><recordid>TN_cdi_proquest_journals_2352709492</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2352709492</sourcerecordid><originalsourceid>FETCH-proquest_journals_23527094923</originalsourceid><addsrcrecordid>eNqNiksLgkAURocoyB7_4UJbhcm3S-mB7YKirVxqrBGdsbkq1K_PRe1bfYdzvhGz1pEXOHHI_fGPg9idshlRyXnoJT632Gmra6lQXQXoAi5oJKoWsq5GBZkwjaBemo4ghBTSWqv7YGt9k1i9SBIcsZVCtWRD-ujxbcPBoFqwSYEVieV352y13503mdMY_ewEtXmpO6OGlLte4EY88RPX--_1AaydQCY</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2352709492</pqid></control><display><type>article</type><title>Dominance of Variant Human Herpesvirus 6 A Among Hemodialysis Patients, Ahvaz, Iran</title><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><creator>Mahmoudvand, Shahab ; Shokri, Somayeh ; Nahid-Samiei, Rahil ; Gholam-Abbas Kaydani ; Makvandi, Manoochehr ; Jalilian, Shahram ; Shahbazian, Heshmatollah ; Shayanpour, Shokouh ; Kimia Makvandi ; Pirmoradi, Roya</creator><creatorcontrib>Mahmoudvand, Shahab ; Shokri, Somayeh ; Nahid-Samiei, Rahil ; Gholam-Abbas Kaydani ; Makvandi, Manoochehr ; Jalilian, Shahram ; Shahbazian, Heshmatollah ; Shayanpour, Shokouh ; Kimia Makvandi ; Pirmoradi, Roya</creatorcontrib><description>Introduction. Hemodialysis (HD) patients are a high-risk population for acquiring blood-borne viruses such as HHV-6. HHV-6 can remain latent in the host cells after primary infection; the reactivation of virus may result complications such as seizure, respiratory failure, hepatitis, and encephalitis. There is a limited report concerning HHV-6 infection in HD patients in Iran. Thus, this study was conducted to determine the frequency of HHV-6 among HD patients.Methods. We determined HHV-6 DNA in sera samples of 84 patients undergoing HD. The DNA was extracted from the sera samples and the presence of HHV-6 DNA variants A and B was evaluated by nested PCR.Results. 52/84 (61.9%) of HD patients were males and 32/84 (38.1%) females. The age ranges of patients were between 18 to 85 years and the mean age was 52 ± 1.52 (± SD) years. Out of 84 sera samples, HHV-6 DNA was detected in 10 (11.9%) participants, including 6/52 (11.5%) in males and 4/32 (12.5%) in females. HHV- 6A was detected in 10/10 (100%) of positive cases. No HHV-6 B was found in HD patients. The distribution of HHV-6A DNA was not significant between genders (P > .05). Out of 84 HD patients, 55 (65.47%) cases were over 50 years, among them 10 (18.18%) cases were positive for HHV-6 A infection (P < .05).Conclusion. The results showed that only HHV-6 DNA variant A was found in 11.9% of HD patients. Regarding the consequence of HHV-6 reactivation, to manage and improve treatment, the screening of HHV-6 DNA test should be implemented for HD patients.</description><identifier>ISSN: 1735-8582</identifier><identifier>EISSN: 1735-8604</identifier><language>eng</language><publisher>Tehran: Iranian Society of Nephrology</publisher><subject>Deoxyribonucleic acid ; DNA ; Hemodialysis ; Infections</subject><ispartof>Iranian journal of kidney diseases, 2019-11, Vol.13 (6), p.404</ispartof><rights>Copyright Iranian Society of Nephrology 2019</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids></links><search><creatorcontrib>Mahmoudvand, Shahab</creatorcontrib><creatorcontrib>Shokri, Somayeh</creatorcontrib><creatorcontrib>Nahid-Samiei, Rahil</creatorcontrib><creatorcontrib>Gholam-Abbas Kaydani</creatorcontrib><creatorcontrib>Makvandi, Manoochehr</creatorcontrib><creatorcontrib>Jalilian, Shahram</creatorcontrib><creatorcontrib>Shahbazian, Heshmatollah</creatorcontrib><creatorcontrib>Shayanpour, Shokouh</creatorcontrib><creatorcontrib>Kimia Makvandi</creatorcontrib><creatorcontrib>Pirmoradi, Roya</creatorcontrib><title>Dominance of Variant Human Herpesvirus 6 A Among Hemodialysis Patients, Ahvaz, Iran</title><title>Iranian journal of kidney diseases</title><description>Introduction. Hemodialysis (HD) patients are a high-risk population for acquiring blood-borne viruses such as HHV-6. HHV-6 can remain latent in the host cells after primary infection; the reactivation of virus may result complications such as seizure, respiratory failure, hepatitis, and encephalitis. There is a limited report concerning HHV-6 infection in HD patients in Iran. Thus, this study was conducted to determine the frequency of HHV-6 among HD patients.Methods. We determined HHV-6 DNA in sera samples of 84 patients undergoing HD. The DNA was extracted from the sera samples and the presence of HHV-6 DNA variants A and B was evaluated by nested PCR.Results. 52/84 (61.9%) of HD patients were males and 32/84 (38.1%) females. The age ranges of patients were between 18 to 85 years and the mean age was 52 ± 1.52 (± SD) years. Out of 84 sera samples, HHV-6 DNA was detected in 10 (11.9%) participants, including 6/52 (11.5%) in males and 4/32 (12.5%) in females. HHV- 6A was detected in 10/10 (100%) of positive cases. No HHV-6 B was found in HD patients. The distribution of HHV-6A DNA was not significant between genders (P > .05). Out of 84 HD patients, 55 (65.47%) cases were over 50 years, among them 10 (18.18%) cases were positive for HHV-6 A infection (P < .05).Conclusion. The results showed that only HHV-6 DNA variant A was found in 11.9% of HD patients. Regarding the consequence of HHV-6 reactivation, to manage and improve treatment, the screening of HHV-6 DNA test should be implemented for HD patients.</description><subject>Deoxyribonucleic acid</subject><subject>DNA</subject><subject>Hemodialysis</subject><subject>Infections</subject><issn>1735-8582</issn><issn>1735-8604</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNqNiksLgkAURocoyB7_4UJbhcm3S-mB7YKirVxqrBGdsbkq1K_PRe1bfYdzvhGz1pEXOHHI_fGPg9idshlRyXnoJT632Gmra6lQXQXoAi5oJKoWsq5GBZkwjaBemo4ghBTSWqv7YGt9k1i9SBIcsZVCtWRD-ujxbcPBoFqwSYEVieV352y13503mdMY_ewEtXmpO6OGlLte4EY88RPX--_1AaydQCY</recordid><startdate>20191101</startdate><enddate>20191101</enddate><creator>Mahmoudvand, Shahab</creator><creator>Shokri, Somayeh</creator><creator>Nahid-Samiei, Rahil</creator><creator>Gholam-Abbas Kaydani</creator><creator>Makvandi, Manoochehr</creator><creator>Jalilian, Shahram</creator><creator>Shahbazian, Heshmatollah</creator><creator>Shayanpour, Shokouh</creator><creator>Kimia Makvandi</creator><creator>Pirmoradi, Roya</creator><general>Iranian Society of Nephrology</general><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>CWDGH</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope></search><sort><creationdate>20191101</creationdate><title>Dominance of Variant Human Herpesvirus 6 A Among Hemodialysis Patients, Ahvaz, Iran</title><author>Mahmoudvand, Shahab ; Shokri, Somayeh ; Nahid-Samiei, Rahil ; Gholam-Abbas Kaydani ; Makvandi, Manoochehr ; Jalilian, Shahram ; Shahbazian, Heshmatollah ; Shayanpour, Shokouh ; Kimia Makvandi ; Pirmoradi, Roya</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-proquest_journals_23527094923</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Deoxyribonucleic acid</topic><topic>DNA</topic><topic>Hemodialysis</topic><topic>Infections</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mahmoudvand, Shahab</creatorcontrib><creatorcontrib>Shokri, Somayeh</creatorcontrib><creatorcontrib>Nahid-Samiei, Rahil</creatorcontrib><creatorcontrib>Gholam-Abbas Kaydani</creatorcontrib><creatorcontrib>Makvandi, Manoochehr</creatorcontrib><creatorcontrib>Jalilian, Shahram</creatorcontrib><creatorcontrib>Shahbazian, Heshmatollah</creatorcontrib><creatorcontrib>Shayanpour, Shokouh</creatorcontrib><creatorcontrib>Kimia Makvandi</creatorcontrib><creatorcontrib>Pirmoradi, Roya</creatorcontrib><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Middle East & Africa Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><jtitle>Iranian journal of kidney diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mahmoudvand, Shahab</au><au>Shokri, Somayeh</au><au>Nahid-Samiei, Rahil</au><au>Gholam-Abbas Kaydani</au><au>Makvandi, Manoochehr</au><au>Jalilian, Shahram</au><au>Shahbazian, Heshmatollah</au><au>Shayanpour, Shokouh</au><au>Kimia Makvandi</au><au>Pirmoradi, Roya</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Dominance of Variant Human Herpesvirus 6 A Among Hemodialysis Patients, Ahvaz, Iran</atitle><jtitle>Iranian journal of kidney diseases</jtitle><date>2019-11-01</date><risdate>2019</risdate><volume>13</volume><issue>6</issue><spage>404</spage><pages>404-</pages><issn>1735-8582</issn><eissn>1735-8604</eissn><abstract>Introduction. Hemodialysis (HD) patients are a high-risk population for acquiring blood-borne viruses such as HHV-6. HHV-6 can remain latent in the host cells after primary infection; the reactivation of virus may result complications such as seizure, respiratory failure, hepatitis, and encephalitis. There is a limited report concerning HHV-6 infection in HD patients in Iran. Thus, this study was conducted to determine the frequency of HHV-6 among HD patients.Methods. We determined HHV-6 DNA in sera samples of 84 patients undergoing HD. The DNA was extracted from the sera samples and the presence of HHV-6 DNA variants A and B was evaluated by nested PCR.Results. 52/84 (61.9%) of HD patients were males and 32/84 (38.1%) females. The age ranges of patients were between 18 to 85 years and the mean age was 52 ± 1.52 (± SD) years. Out of 84 sera samples, HHV-6 DNA was detected in 10 (11.9%) participants, including 6/52 (11.5%) in males and 4/32 (12.5%) in females. HHV- 6A was detected in 10/10 (100%) of positive cases. No HHV-6 B was found in HD patients. The distribution of HHV-6A DNA was not significant between genders (P > .05). Out of 84 HD patients, 55 (65.47%) cases were over 50 years, among them 10 (18.18%) cases were positive for HHV-6 A infection (P < .05).Conclusion. The results showed that only HHV-6 DNA variant A was found in 11.9% of HD patients. Regarding the consequence of HHV-6 reactivation, to manage and improve treatment, the screening of HHV-6 DNA test should be implemented for HD patients.</abstract><cop>Tehran</cop><pub>Iranian Society of Nephrology</pub></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1735-8582 |
| ispartof | Iranian journal of kidney diseases, 2019-11, Vol.13 (6), p.404 |
| issn | 1735-8582 1735-8604 |
| language | eng |
| recordid | cdi_proquest_journals_2352709492 |
| source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Deoxyribonucleic acid DNA Hemodialysis Infections |
| title | Dominance of Variant Human Herpesvirus 6 A Among Hemodialysis Patients, Ahvaz, Iran |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-05T11%3A35%3A12IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Dominance%20of%20Variant%20Human%20Herpesvirus%206%20A%20Among%20Hemodialysis%20Patients,%20Ahvaz,%20Iran&rft.jtitle=Iranian%20journal%20of%20kidney%20diseases&rft.au=Mahmoudvand,%20Shahab&rft.date=2019-11-01&rft.volume=13&rft.issue=6&rft.spage=404&rft.pages=404-&rft.issn=1735-8582&rft.eissn=1735-8604&rft_id=info:doi/&rft_dat=%3Cproquest%3E2352709492%3C/proquest%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2352709492&rft_id=info:pmid/&rfr_iscdi=true |