Repeated stereotactic radiosurgery (SRS) using a non-coplanar mono-isocenter (HyperArc™) technique versus upfront whole-brain radiotherapy (WBRT): a matched-pair analysis

Stereotactic radiosurgery (SRS) is an effective treatment option for multiple brain metastases (BMs). Modern mono-isocentric techniques allow the delivery of multiple stereotactic courses, in the event of intracranial failure. Nevertheless, limited data on effectiveness and toxicity have been report...

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Veröffentlicht in:	Clinical & experimental metastasis 2020-02, Vol.37 (1), p.77-83
Hauptverfasser:	Nicosia, Luca, Figlia, Vanessa, Mazzola, Rosario, Napoli, Giuseppe, Giaj-Levra, Niccolò, Ricchetti, Francesco, Rigo, Michele, Lunardi, Gianluigi, Tomasini, Davide, Bonù, Marco L., Corradini, Stefanie, Ruggieri, Ruggero, Alongi, Filippo
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biomedical and Life Sciences Biomedicine Brain Brain - pathology Brain - radiation effects Brain cancer Brain Neoplasms - mortality Brain Neoplasms - radiotherapy Brain Neoplasms - secondary Cancer Research Cranial Irradiation - adverse effects Cranial Irradiation - methods Disease Progression Female Follow-Up Studies Hematology Humans Kaplan-Meier Estimate Male Matched-Pair Analysis Metastases Metastasis Middle Aged Necrosis - epidemiology Necrosis - etiology Neoplasm Recurrence, Local - mortality Neoplasm Recurrence, Local - pathology Neoplasm Recurrence, Local - radiotherapy Oncology Patients Progression-Free Survival Radiation Injuries - epidemiology Radiation Injuries - etiology Radiation therapy Radiology Radiosurgery Radiosurgery - adverse effects Radiosurgery - methods Research Paper Retreatment - adverse effects Retreatment - methods Retrospective Studies Surgery Surgical Oncology Survival Toxicity Treatment Outcome
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