Enhanced matrix synthesis and in vitro formation of cartilage-like tissue by genetically modified chondroytes expressing BMP-7

Bone morphogenic protein-7 (BMP-7) supports ectopic cartilage and bone formation, is expressed in normal articular cartilage, and increases matrix synthesis in chondrocytes. Based on this knowledge, we hypothesized that an adenovirus (Ad) vector encoding human BMP-7 could be used to modify chondrocy...

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Veröffentlicht in:	Journal of orthopaedic research 2001-09, Vol.19 (5), p.751
Hauptverfasser:	Hidaka, Chisa, Mannix Quitoriano, Warren, Russell F, Crystal, Ronald G
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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