Pretreatment of Rats with an Allosteric Luteinizing Hormone Receptor Agonist Enhances Chorionic Gonadotropin-Induced Stimulation of Testosterone Production

In clinical practice, luteinizing hormone (LH) and chorionic gonadotropin (CG) are used as activators of the LH receptor, leading to the stimulation of gonadal steroidogenesis. However, high doses of gonadotropin preparations cause a number of side effects. Here we demonstrate that the pretreatment...

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Veröffentlicht in:	Journal of evolutionary biochemistry and physiology 2019-11, Vol.55 (6), p.510-514
Hauptverfasser:	Shpakov, A. O., Bakhtyukov, A. A., Dar’in, D. V., Derkach, K. V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Agonists Allosteric properties Animal Physiology Biochemistry Biomedical and Life Sciences Chorionic gonadotropin Chromosome 3 Evolutionary Biology Gene expression Gonadotropins Life Sciences Luteinizing hormone Pituitary (anterior) Short Communications Steroidogenesis Testosterone Transcription activation
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