IRAK2 is associated with systemic lupus erythematosus risk

Introduction Interleukin-1 receptor-associated kinases (IRAKs) are serine-threonine kinases involved in toll-like receptor and interleukin-1 signaling pathways. They play a key role in inflammation and innate immunity. IRAKs have been previously incriminated in autoimmune diseases such as systemic l...

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Veröffentlicht in:	Clinical rheumatology 2020-02, Vol.39 (2), p.419-424
Hauptverfasser:	Boumiza, Asma, Zemni, Ramzi, Sghiri, Rim, Idriss, Nadia, Hassine, Hana Ben, Chabchoub, Elyes, Mzabi, Anis, Ghannouchi, Neirouz, Bouajina, Elyes, Ben Hadj Slama, Foued
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alleles Autoimmune diseases Case-Control Studies Cytokines Female Genetic Predisposition to Disease Genotypes Haplotypes Humans Innate immunity Interleukin 1 Interleukin-1 Receptor-Associated Kinases - genetics IRAK protein Linkage disequilibrium Lupus Lupus Erythematosus, Systemic - genetics Male Medicine Medicine & Public Health Middle Aged Original Article Polymerase chain reaction Polymorphism, Single Nucleotide Rheumatoid arthritis Rheumatology Serine Systemic lupus erythematosus Threonine Toll-like receptors Young Adult
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