Effects of lipophilicity and functional groups of synthetic cannabinoids on their blood concentrations and urinary excretion

•Fifteen synthetic cannabinoids (SCs) were determined in the urine or blood from 31 SC users who were involved in car crashes.•Lipophilic SCs were not detected in urine while water-soluble SCs were often detected.•Range of lipophilic SCs concentrations in blood were much narrower than that of water-...

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Veröffentlicht in:	Forensic science international 2020-02, Vol.307, p.110106, Article 110106
Hauptverfasser:	Kakehashi, Hidenao, Shima, Noriaki, Ishikawa, Akari, Nitta, Atsushi, Asai, Ryutaro, Wada, Misato, Nakano, Shihoko, Matsuta, Shuntaro, Sasaki, Keiko, Kamata, Hiroe, Kamata, Tooru, Nishioka, Hiroshi, Miki, Akihiro, Katagi, Munehiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Analogs Blood Cannabinoids Cannabinoids - blood Cannabinoids - pharmacokinetics Cannabinoids - urine Chemicals Chromatography, Liquid Crashes Drivers Driving Excretion Forensic sciences Functional groups Humans Indoles LC–MS/MS Leucine Lipophilicity Liquid chromatography Mass spectrometry Mass spectroscopy Mathematical analysis Naphthol Octanol Octanols - chemistry Pharmacokinetics Synthetic cannabinoids Tandem Mass Spectrometry Traffic accidents Urine Valine Water - chemistry
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