Phenolic Compounds from Butia odorata (Barb. Rodr.) Noblick Fruit and Its Antioxidant and Antitumor Activities
This study evaluated the antioxidant activity and total phenolic content (TPC) of Butia odorata fruit extracted with different solvents, as well as the phenolic composition using UHPLC-MS/MS analysis. In addition, the antitumor potential of B. odorata fruit against various cancer cell lines (Caco-2,...
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| Veröffentlicht in: | Food analytical methods 2020, Vol.13 (1), p.61-68 |
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| creator | Boeing, Joana Schuelter Barizão, Érica Oliveira Rotta, Eliza Mariane Volpato, Hélito Nakamura, Celso Vataru Maldaner, Liane Visentainer, Jesuí Vergílio |
| description | This study evaluated the antioxidant activity and total phenolic content (TPC) of
Butia odorata
fruit extracted with different solvents, as well as the phenolic composition using UHPLC-MS/MS analysis. In addition, the antitumor potential of
B. odorata
fruit against various cancer cell lines (Caco-2, HeLa, SiHa, C33a) was evaluated for the first time. The TPC and antioxidant activity (DPPH
•
and ORAC assays) varied according to the extraction solvents, with the highest values obtained for the methanol:water (80:20,
v
/
v
) extracts. Thirteen phenolic compounds were quantified in the ethanol:water (80:20,
v
/
v
) extracts of
B. odorata
fruit by UHPLC-MS/MS, with the main compounds identified as (+)-catechin (259 ± 18 mg kg
−1
), (−)-epicatechin (211 ± 12 mg kg
−1
) and rutin (161 ± 2 mg kg
−1
). Sinapic and ellagic acids,
trans
-resveratrol, naringenin, and apigenin were reported in
B. odarata
fruit for the first time. Furthermore, the
B. odorata
fruit showed antitumor activity against cervical cancer cell lines (SiHa and C33a), providing preliminary evidence for further assessment of its anticancer potential. |
| doi_str_mv | 10.1007/s12161-019-01515-6 |
| format | Article |
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Butia odorata
fruit extracted with different solvents, as well as the phenolic composition using UHPLC-MS/MS analysis. In addition, the antitumor potential of
B. odorata
fruit against various cancer cell lines (Caco-2, HeLa, SiHa, C33a) was evaluated for the first time. The TPC and antioxidant activity (DPPH
•
and ORAC assays) varied according to the extraction solvents, with the highest values obtained for the methanol:water (80:20,
v
/
v
) extracts. Thirteen phenolic compounds were quantified in the ethanol:water (80:20,
v
/
v
) extracts of
B. odorata
fruit by UHPLC-MS/MS, with the main compounds identified as (+)-catechin (259 ± 18 mg kg
−1
), (−)-epicatechin (211 ± 12 mg kg
−1
) and rutin (161 ± 2 mg kg
−1
). Sinapic and ellagic acids,
trans
-resveratrol, naringenin, and apigenin were reported in
B. odarata
fruit for the first time. Furthermore, the
B. odorata
fruit showed antitumor activity against cervical cancer cell lines (SiHa and C33a), providing preliminary evidence for further assessment of its anticancer potential.</description><identifier>ISSN: 1936-9751</identifier><identifier>EISSN: 1936-976X</identifier><identifier>DOI: 10.1007/s12161-019-01515-6</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Analytical Chemistry ; Anticancer properties ; Antioxidants ; Antitumor activity ; Biotechnology ; Catechin ; Cervical cancer ; Cervix ; Chemistry ; Chemistry and Materials Science ; Chemistry/Food Science ; Epicatechin ; Ethanol ; Evaluation ; Food Science ; Fruits ; Microbiology ; Naringenin ; Phenolic compounds ; Phenols ; Resveratrol ; Rutin ; Solvents ; Tumor cell lines</subject><ispartof>Food analytical methods, 2020, Vol.13 (1), p.61-68</ispartof><rights>Springer Science+Business Media, LLC, part of Springer Nature 2019</rights><rights>2019© Springer Science+Business Media, LLC, part of Springer Nature 2019</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c319t-81d34be58c8903a1a0a312714e22e11bac0c7e44820c62b8a02ba311ac35ba553</citedby><cites>FETCH-LOGICAL-c319t-81d34be58c8903a1a0a312714e22e11bac0c7e44820c62b8a02ba311ac35ba553</cites><orcidid>0000-0001-6761-2157</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s12161-019-01515-6$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s12161-019-01515-6$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27903,27904,41467,42536,51297</link.rule.ids></links><search><creatorcontrib>Boeing, Joana Schuelter</creatorcontrib><creatorcontrib>Barizão, Érica Oliveira</creatorcontrib><creatorcontrib>Rotta, Eliza Mariane</creatorcontrib><creatorcontrib>Volpato, Hélito</creatorcontrib><creatorcontrib>Nakamura, Celso Vataru</creatorcontrib><creatorcontrib>Maldaner, Liane</creatorcontrib><creatorcontrib>Visentainer, Jesuí Vergílio</creatorcontrib><title>Phenolic Compounds from Butia odorata (Barb. Rodr.) Noblick Fruit and Its Antioxidant and Antitumor Activities</title><title>Food analytical methods</title><addtitle>Food Anal. Methods</addtitle><description>This study evaluated the antioxidant activity and total phenolic content (TPC) of
Butia odorata
fruit extracted with different solvents, as well as the phenolic composition using UHPLC-MS/MS analysis. In addition, the antitumor potential of
B. odorata
fruit against various cancer cell lines (Caco-2, HeLa, SiHa, C33a) was evaluated for the first time. The TPC and antioxidant activity (DPPH
•
and ORAC assays) varied according to the extraction solvents, with the highest values obtained for the methanol:water (80:20,
v
/
v
) extracts. Thirteen phenolic compounds were quantified in the ethanol:water (80:20,
v
/
v
) extracts of
B. odorata
fruit by UHPLC-MS/MS, with the main compounds identified as (+)-catechin (259 ± 18 mg kg
−1
), (−)-epicatechin (211 ± 12 mg kg
−1
) and rutin (161 ± 2 mg kg
−1
). Sinapic and ellagic acids,
trans
-resveratrol, naringenin, and apigenin were reported in
B. odarata
fruit for the first time. Furthermore, the
B. odorata
fruit showed antitumor activity against cervical cancer cell lines (SiHa and C33a), providing preliminary evidence for further assessment of its anticancer potential.</description><subject>Analytical Chemistry</subject><subject>Anticancer properties</subject><subject>Antioxidants</subject><subject>Antitumor activity</subject><subject>Biotechnology</subject><subject>Catechin</subject><subject>Cervical cancer</subject><subject>Cervix</subject><subject>Chemistry</subject><subject>Chemistry and Materials Science</subject><subject>Chemistry/Food Science</subject><subject>Epicatechin</subject><subject>Ethanol</subject><subject>Evaluation</subject><subject>Food Science</subject><subject>Fruits</subject><subject>Microbiology</subject><subject>Naringenin</subject><subject>Phenolic compounds</subject><subject>Phenols</subject><subject>Resveratrol</subject><subject>Rutin</subject><subject>Solvents</subject><subject>Tumor cell lines</subject><issn>1936-9751</issn><issn>1936-976X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNp9kE9LAzEQxYMoWKtfwFPAix62ZpLd7e6xFquFoiIK3sJsNtXUblKTrOi3d-uK3jwM84ffewOPkGNgI2BsfB6AQw4Jg7KrDLIk3yEDKEWelOP8afd3zmCfHISwYixnKfABsXcv2rq1UXTqmo1rbR3o0ruGXrTRIHW18xiRnl6gr0b03tV-dEZvXNUpXunMtyZStDWdx0AnNhr3YWq0_W27x7Zxnk5UNO8mGh0Oyd4S10Ef_fQheZxdPkyvk8Xt1Xw6WSRKQBmTAmqRVjorVFEygYAMBfAxpJpzDVChYmqs07TgTOW8KpDxqiMAlcgqzDIxJCe978a7t1aHKFeu9bZ7KblIBS8AWN5RvKeUdyF4vZQbbxr0nxKY3OYq-1xll6v8zlVuRaIXhQ62z9r_Wf-j-gLRgXpp</recordid><startdate>2020</startdate><enddate>2020</enddate><creator>Boeing, Joana Schuelter</creator><creator>Barizão, Érica Oliveira</creator><creator>Rotta, Eliza Mariane</creator><creator>Volpato, Hélito</creator><creator>Nakamura, Celso Vataru</creator><creator>Maldaner, Liane</creator><creator>Visentainer, Jesuí Vergílio</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>AAYXX</scope><scope>CITATION</scope><orcidid>https://orcid.org/0000-0001-6761-2157</orcidid></search><sort><creationdate>2020</creationdate><title>Phenolic Compounds from Butia odorata (Barb. Rodr.) Noblick Fruit and Its Antioxidant and Antitumor Activities</title><author>Boeing, Joana Schuelter ; Barizão, Érica Oliveira ; Rotta, Eliza Mariane ; Volpato, Hélito ; Nakamura, Celso Vataru ; Maldaner, Liane ; Visentainer, Jesuí Vergílio</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c319t-81d34be58c8903a1a0a312714e22e11bac0c7e44820c62b8a02ba311ac35ba553</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Analytical Chemistry</topic><topic>Anticancer properties</topic><topic>Antioxidants</topic><topic>Antitumor activity</topic><topic>Biotechnology</topic><topic>Catechin</topic><topic>Cervical cancer</topic><topic>Cervix</topic><topic>Chemistry</topic><topic>Chemistry and Materials Science</topic><topic>Chemistry/Food Science</topic><topic>Epicatechin</topic><topic>Ethanol</topic><topic>Evaluation</topic><topic>Food Science</topic><topic>Fruits</topic><topic>Microbiology</topic><topic>Naringenin</topic><topic>Phenolic compounds</topic><topic>Phenols</topic><topic>Resveratrol</topic><topic>Rutin</topic><topic>Solvents</topic><topic>Tumor cell lines</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Boeing, Joana Schuelter</creatorcontrib><creatorcontrib>Barizão, Érica Oliveira</creatorcontrib><creatorcontrib>Rotta, Eliza Mariane</creatorcontrib><creatorcontrib>Volpato, Hélito</creatorcontrib><creatorcontrib>Nakamura, Celso Vataru</creatorcontrib><creatorcontrib>Maldaner, Liane</creatorcontrib><creatorcontrib>Visentainer, Jesuí Vergílio</creatorcontrib><collection>CrossRef</collection><jtitle>Food analytical methods</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Boeing, Joana Schuelter</au><au>Barizão, Érica Oliveira</au><au>Rotta, Eliza Mariane</au><au>Volpato, Hélito</au><au>Nakamura, Celso Vataru</au><au>Maldaner, Liane</au><au>Visentainer, Jesuí Vergílio</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Phenolic Compounds from Butia odorata (Barb. Rodr.) Noblick Fruit and Its Antioxidant and Antitumor Activities</atitle><jtitle>Food analytical methods</jtitle><stitle>Food Anal. Methods</stitle><date>2020</date><risdate>2020</risdate><volume>13</volume><issue>1</issue><spage>61</spage><epage>68</epage><pages>61-68</pages><issn>1936-9751</issn><eissn>1936-976X</eissn><abstract>This study evaluated the antioxidant activity and total phenolic content (TPC) of
Butia odorata
fruit extracted with different solvents, as well as the phenolic composition using UHPLC-MS/MS analysis. In addition, the antitumor potential of
B. odorata
fruit against various cancer cell lines (Caco-2, HeLa, SiHa, C33a) was evaluated for the first time. The TPC and antioxidant activity (DPPH
•
and ORAC assays) varied according to the extraction solvents, with the highest values obtained for the methanol:water (80:20,
v
/
v
) extracts. Thirteen phenolic compounds were quantified in the ethanol:water (80:20,
v
/
v
) extracts of
B. odorata
fruit by UHPLC-MS/MS, with the main compounds identified as (+)-catechin (259 ± 18 mg kg
−1
), (−)-epicatechin (211 ± 12 mg kg
−1
) and rutin (161 ± 2 mg kg
−1
). Sinapic and ellagic acids,
trans
-resveratrol, naringenin, and apigenin were reported in
B. odarata
fruit for the first time. Furthermore, the
B. odorata
fruit showed antitumor activity against cervical cancer cell lines (SiHa and C33a), providing preliminary evidence for further assessment of its anticancer potential.</abstract><cop>New York</cop><pub>Springer US</pub><doi>10.1007/s12161-019-01515-6</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0001-6761-2157</orcidid></addata></record> |
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| subjects | Analytical Chemistry Anticancer properties Antioxidants Antitumor activity Biotechnology Catechin Cervical cancer Cervix Chemistry Chemistry and Materials Science Chemistry/Food Science Epicatechin Ethanol Evaluation Food Science Fruits Microbiology Naringenin Phenolic compounds Phenols Resveratrol Rutin Solvents Tumor cell lines |
| title | Phenolic Compounds from Butia odorata (Barb. Rodr.) Noblick Fruit and Its Antioxidant and Antitumor Activities |
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