Antiviral Activity of a New Class of Chemically Modified Antisense Oligonucleotides against Influenza А Virus

— The paper reports the synthesis of a series of antisense oligonucleotides (aONs) directed against different segments of the influenza A virus genome (H1N1) and screening of their antiviral activity in the influenza A virus (H1N1)/MDCK cells and influenza A virus (H1N1)/A549 cells systems. The resu...

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Veröffentlicht in:	Russian journal of bioorganic chemistry 2019-11, Vol.45 (6), p.774-782
Hauptverfasser:	Markov, A. V., Kupryushkin, M. S., Goncharova, E. P., Amirkhanov, R. N., Vasilyeva, S. V., Pyshnyi, D. V., Zenkova, M. A., Logashenko, E. B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Biological effects Biomedical and Life Sciences Biomedicine Bioorganic Chemistry Genomes Influenza Life Sciences Oligonucleotides Organic Chemistry Screening Viruses
Online-Zugang:	Volltext
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