Tegaserod (Zelnorm) for irritable bowel syndrome
Tegaserod (Zelnorm) is the first treatment approved by the US Food and Drug Administration for the short-term management of constipation-predominant irritable bowel syndrome (IBS) in women. A partial agonist of serotonin subtype-4 receptors, tegaserod stimulates peristalsis, increases intestinal sec...
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Veröffentlicht in: | American family physician 2004-01, Vol.69 (2), p.363 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Tegaserod (Zelnorm) is the first treatment approved by the US Food and Drug Administration for the short-term management of constipation-predominant irritable bowel syndrome (IBS) in women. A partial agonist of serotonin subtype-4 receptors, tegaserod stimulates peristalsis, increases intestinal secretion, and may alter associated pain. In contrast, alosetron (Lotronex) is available under restricted conditions of use for diarrhea-predominant IBS. |
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ISSN: | 0002-838X |