Regiodivergent Intramolecular Nucleophilic Addition of Ketimines for the Diverse Synthesis of Azacycles

Azacycles such as indoles and tetrahydroquinolines are privileged structures in drug development. Reported here is an unprecedented regiodivergent intramolecular nucleophilic addition reaction of imines as a flexible approach to access N‐functionalized indoles and tetrahydroquinolines, by the contro...

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Veröffentlicht in:	Angewandte Chemie International Edition 2020-01, Vol.59 (4), p.1634-1643
Hauptverfasser:	Wang, Yu‐Hui, Tian, Jun‐Song, Tan, Peng‐Wei, Cao, Qiang, Zhang, Xue‐Xin, Cao, Zhong‐Yan, Zhou, Feng, Wang, Xin, Zhou, Jian
Format:	Artikel
Sprache:	eng
Schlagworte:	Aniline Chemical synthesis Drug development Enantiomers heterocycles Imines Indoles Ketoesters organocatalysis reaction mechanisms synthetic methods
Online-Zugang:	Volltext
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