Neutrophil extracellular traps promote liver micrometastasis in pancreatic ductal adenocarcinoma via the activation of cancer‑associated fibroblasts

Cancer‑associated fibroblasts (CAFs) promote the progression of pancreatic ductal adenocarcinoma (PDAC) via tumor‑stromal interactions. Neutrophil extracellular traps (NETs) are extracellular DNA meshworks released from neutrophils together with proteolytic enzymes against foreign pathogens. Emergin...

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Veröffentlicht in:	International journal of oncology 2020-02, Vol.56 (2), p.596-605
Hauptverfasser:	Takesue, Shin, Ohuchida, Kenoki, Shinkawa, Tomohiko, Otsubo, Yoshiki, Matsumoto, Sokichi, Sagara, Akiko, Yonenaga, Akiko, Ando, Yohei, Kibe, Shin, Nakayama, Hiromichi, Iwamoto, Chika, Shindo, Koji, Moriyama, Taiki, Nakata, Kohei, Miyasaka, Yoshihiro, Ohtsuka, Takao, Toma, Hiroki, Tominaga, Yohei, Mizumoto, Kazuhiro, Hashizume, Makoto, Nakamura, Masafumi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma Analysis Aspartic proteases Bone marrow Cancer cells Cancer metastasis Cancer research Cytokines Deoxyribonucleic acid DNA Enzymes Experiments Fibroblasts Immunoglobulins Infectious diseases Liver Liver cancer Metastasis Neutrophils Nucleases Pancreatic cancer Pathogenic microorganisms Proteases Tumors
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