Cytotoxic effects of a sesquiterpene β-elemene on THP-1 leukemia cells is mediated via crosstalk between beclin-1 mediated autophagy and caspase-dependent apoptosis

[Display omitted] •β- elemene was tested for its cytotoxic effect against THP-1 cells via MTT assay.•Expression of mRNAs of certain autophagy and apoptotic genes were evaluated by quantitative PCR.•There is a crosstalk between autophagy and apoptosis as determined by mRNA expressions. β- elemene ext...

Ausführliche Beschreibung