Expansion of Rare CD8+CD28-CD11b- T Cells With Impaired Effector Functions in HIV-1-Infected Patients

The decline in the number of CD4 T cells in HIV-1-infected patients is known to be related to the increased number of CD8CD28 T cells. In this paper, we show that CD8CD28- T cells from HIV-positive patients have an impaired capability to interact with human endothelial cells. This is due to the dram...

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Veröffentlicht in:	Journal of acquired immune deficiency syndromes (1999) 2000-08, Vol.24 (5), p.465-474
Hauptverfasser:	Caruso, Arnaldo, Fiorentini, Simona, Licenziati, Stefano, Alessandri, Giulio, Ricotta, Doris, Imberti, Luisa, Signorini, Simona, Armenta-Solis, Adakatia, Garrafa, Emirena, Balsari, Andrea, Turano, Adolfo
Format:	Artikel
Sprache:	eng
Schlagworte:	Case-Control Studies CD28 Antigens - blood CD28 Antigens - immunology CD4-CD8 Ratio CD8-Positive T-Lymphocytes - immunology Cells Cytokines - biosynthesis Cytotoxicity Tests, Immunologic Female Flow Cytometry HIV HIV Infections - immunology HIV-1 Human immunodeficiency virus Humans Lymphatic system Lymphocyte Activation Macrophage-1 Antigen - blood Macrophage-1 Antigen - immunology Male Membrane Glycoproteins - biosynthesis Perforin Pore Forming Cytotoxic Proteins Receptors, Antigen, T-Cell, alpha-beta - blood Receptors, Antigen, T-Cell, alpha-beta - chemistry Receptors, Antigen, T-Cell, alpha-beta - genetics Tumors
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