Two instantaneous fluorogenic steps for detection of nanomolar amyloid beta monomer and its interaction with stoichiometric copper(II) ion

[Display omitted] •Fluorogenic response from SEA-SC2 and AuNP combination is better than each of them.•First report of fluorogenic response from 10 to 60 nM Aβ monomers at pH 7.4.•Second step fluorogenicity is due to the interactions with stoichiometric Cu(II).•Both fluorogenic steps are observed ju...

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Veröffentlicht in:	Sensors and actuators. B, Chemical Chemical, 2020-01, Vol.303, p.127086, Article 127086
Hauptverfasser:	Saini, Meenaxi, Sadhu, Kalyan K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aβ peptide Cerebrospinal fluid Copper Copper compounds Cu(II) Dye Fluorescence Fluorescence enhancement Monomers Nanoparticle Nanoparticles Organic chemistry Peptides Serum albumin Stoichiometry
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