Relationship between metabolic syndrome and acylated/desacylated ghrelin ratio in patients with schizophrenia under olanzapine medication

Background: Ghrelin is a peptide hormone that mediates glucose homeostasis and lipid metabolism. Acylated ghrelin (AG) and desacylated ghrelin (DAG) are the two main forms of ghrelin, which have opposing roles in energy homeostasis. The AG/DAG ratio has been proposed to be associated with metabolic...

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Veröffentlicht in:	Journal of psychopharmacology (Oxford) 2020-01, Vol.34 (1), p.86-92
Hauptverfasser:	Wu, Tzu-Hua, Chiu, Chih-Chiang, Goh, Kah Kheng, Chen, Po-Yu, Huang, Ming-Chyi, Chen, Chun-Hsin, Lu, Mong-Liang
Format:	Artikel
Sprache:	eng
Schlagworte:	Acylation - drug effects Adult Antipsychotics Body mass Body mass index Case-Control Studies Drug therapy Energy balance Enzyme-linked immunosorbent assay Female Ghrelin Ghrelin - blood Glucose metabolism Homeostasis Humans Insulin Lipid metabolism Male Mental disorders Metabolic disorders Metabolic syndrome Metabolic Syndrome - blood Metabolic Syndrome - complications Olanzapine Olanzapine - therapeutic use Population studies Regression analysis Schizophrenia Schizophrenia - blood Schizophrenia - complications Schizophrenia - drug therapy Serum levels Sex differences Sex Factors
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