Fabrication of Low Temperature Carbonated Hydroxyapatite Porous Scaffolds for Bone Tissue Engineering Applications
Three-dimensional (3D) porous carbonated hydroxyapatite (CHA) scaffolds were successfully prepared using polyurethane (PU) replication technique. Two sets of porous scaffolds were prepared using as-synthesized and as-calcined CHA powder as the main component of the slurry. The effect of the conditio...
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| Veröffentlicht in: | Key engineering materials 2019-12, Vol.829, p.167-172 |
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| creator | Mohd Noor, Ahmad Fauzi Baba Ismail, Yanny Marliana Mohd Noor, Muhammad Syazwan |
| description | Three-dimensional (3D) porous carbonated hydroxyapatite (CHA) scaffolds were successfully prepared using polyurethane (PU) replication technique. Two sets of porous scaffolds were prepared using as-synthesized and as-calcined CHA powder as the main component of the slurry. The effect of the condition of starting material was investigated in terms of structure, phase purity, crystallinity and morphology of the fabricated porous scaffolds. Regardless of the condition of starting material used, the porous scaffolds fabricated was single phase B-type CHA and free of secondary phases. Interestingly, scaffolds made of as-calcined CHA powder (SC scaffolds) showed a smoother surface and more solidified struts when compared to as-synthesized CHA powder (SA scaffolds). This is attributed to the state of semi-crystalline phase of the as-calcined powder being amorphous phase. SC scaffold was found to be better scaffold with respect to handling, compaction strength and microstructure with better strut properties. |
| doi_str_mv | 10.4028/www.scientific.net/KEM.829.167 |
| format | Article |
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Two sets of porous scaffolds were prepared using as-synthesized and as-calcined CHA powder as the main component of the slurry. The effect of the condition of starting material was investigated in terms of structure, phase purity, crystallinity and morphology of the fabricated porous scaffolds. Regardless of the condition of starting material used, the porous scaffolds fabricated was single phase B-type CHA and free of secondary phases. Interestingly, scaffolds made of as-calcined CHA powder (SC scaffolds) showed a smoother surface and more solidified struts when compared to as-synthesized CHA powder (SA scaffolds). This is attributed to the state of semi-crystalline phase of the as-calcined powder being amorphous phase. SC scaffold was found to be better scaffold with respect to handling, compaction strength and microstructure with better strut properties.</description><identifier>ISSN: 1013-9826</identifier><identifier>ISSN: 1662-9795</identifier><identifier>EISSN: 1662-9795</identifier><identifier>DOI: 10.4028/www.scientific.net/KEM.829.167</identifier><language>eng</language><publisher>Zurich: Trans Tech Publications Ltd</publisher><subject>Biomedical materials ; Carbonation ; Crystal structure ; Crystallinity ; Hydroxyapatite ; Low temperature ; Morphology ; Polyurethane resins ; Porous materials ; Roasting ; Scaffolds ; Slurries ; Struts ; Synthesis ; Tissue engineering</subject><ispartof>Key engineering materials, 2019-12, Vol.829, p.167-172</ispartof><rights>2020 Trans Tech Publications Ltd</rights><rights>Copyright Trans Tech Publications Ltd. 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SC scaffold was found to be better scaffold with respect to handling, compaction strength and microstructure with better strut properties.</description><subject>Biomedical materials</subject><subject>Carbonation</subject><subject>Crystal structure</subject><subject>Crystallinity</subject><subject>Hydroxyapatite</subject><subject>Low temperature</subject><subject>Morphology</subject><subject>Polyurethane resins</subject><subject>Porous materials</subject><subject>Roasting</subject><subject>Scaffolds</subject><subject>Slurries</subject><subject>Struts</subject><subject>Synthesis</subject><subject>Tissue engineering</subject><issn>1013-9826</issn><issn>1662-9795</issn><issn>1662-9795</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNqNkF1r2zAUhs3YoF23_yAY7M6OjhRL9s1YFtIPmrLB0mshy8edSiJ5kkyaf1-VBHLbq_PCeXleeIriO9BqTlkz2-_3VTQWXbKDNZXDNLtfPVQNaysQ8kNxCUKwspVt_TFnCrxsGyYuis8xPlPKoYH6sgjXugvW6GS9I34ga78nG9yNGHSaApKlDp13OmFPbg998C8HPeZyQvLHBz9F8tfoYfDbPpLBB_LLOyQbG-OEZOWerEMM1j2RxThuTyvxS_Fp0NuIX0_3qni8Xm2Wt-X6983dcrEuDQMqSyZAGiP7nlE-lz2nBpuuA9bwFkDLZkCNpsc2f3uEFkQn-LyWMK8BuRYdvyq-Hblj8P8njEk9-ym4PKkY5wxkzUWbWz-OLRN8jAEHNQa70-GggKo3zyp7VmfPKntW2bPKnlX2nAE_j4AUtIsJzb_zzjsRr_CMkQw</recordid><startdate>20191230</startdate><enddate>20191230</enddate><creator>Mohd Noor, Ahmad Fauzi</creator><creator>Baba Ismail, Yanny Marliana</creator><creator>Mohd Noor, Muhammad Syazwan</creator><general>Trans Tech Publications Ltd</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7SR</scope><scope>8BQ</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>ABJCF</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>F28</scope><scope>FR3</scope><scope>HCIFZ</scope><scope>JG9</scope><scope>KB.</scope><scope>L6V</scope><scope>M7S</scope><scope>PDBOC</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PTHSS</scope></search><sort><creationdate>20191230</creationdate><title>Fabrication of Low Temperature Carbonated Hydroxyapatite Porous Scaffolds for Bone Tissue Engineering Applications</title><author>Mohd Noor, Ahmad Fauzi ; 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| subjects | Biomedical materials Carbonation Crystal structure Crystallinity Hydroxyapatite Low temperature Morphology Polyurethane resins Porous materials Roasting Scaffolds Slurries Struts Synthesis Tissue engineering |
| title | Fabrication of Low Temperature Carbonated Hydroxyapatite Porous Scaffolds for Bone Tissue Engineering Applications |
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