PP57 Outcomes On Transcatheter Aortic Valve Implantation
Copyright © Cambridge University Press 20192019Cambridge University PressIntroductionSevere aortic stenosis with symptoms or left ventricular dysfunction has commonly a poor prognosis and therefore, aortic valve replacement is usually performed for patients aiming at improving their functional class...
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Veröffentlicht in: | International journal of technology assessment in health care 2019, Vol.35 (S1), p.47-48 |
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creator | Soares dos Santos, Augusto Cesar Horta, Maria da Glória Cruvinel Carvalho, Lélia Maria de Almeida Rodrigues, Luíza Avelar, Sandra de Oliveira Sapori Fernandes, Mariana Scherrer, Luciano Rios Biscione, Fernando Martin Kelles, Silvana Marcia |
description | Copyright © Cambridge University Press 20192019Cambridge University PressIntroductionSevere aortic stenosis with symptoms or left ventricular dysfunction has commonly a poor prognosis and therefore, aortic valve replacement is usually performed for patients aiming at improving their functional class and survival rate.MethodsThis retrospective study evaluated a convenience sample of patients at high risk for open surgery for the correction of aortic valve dysfunction treated with TAVI from 2013 to 2018. Data from a private healthcare organization in Belo Horizonte, Brazil were used to assess all-cause mortality. Continuous variables were expressed as mean and standard deviation. Cox proportional regression model and Log-Rank test were used to adjust the survival curve.ResultsFifty-two patients were included in the study (mean 83 ± 5.7 years of age, range 67 to 93 years; female 55.8 percent). Patients were characterized by: left ventricular ejection fraction (n = 30; mean 52.9 percent, range 26 to 81 percent); aortic valve area (n = 36; mean 0.68 cm2, range 0.4 to 1.2 cm2); left atrium size (n = 14; range 30 to 61 ml/m2); pulmonary artery pressure (n = 20; mean 53 mmHg, range 31 to 70 mmHg). Death occurred in 19 patients during the follow-up period (mean 8.4 months, range 0 to 60 months). Nine deaths occurred within the first 30 days of follow-up (17.3 percent) and 14 (26.9 percent) in the first year. Stroke occurred in three patients (5.8 percent) in the post-implant period. A pacemaker device was required for nine patients (17.3 percent).ConclusionsTranscatheter aortic valve implantation (TAVI) has become an alternative to surgical aortic valve replacement for patients at high risk for surgery. Real-world studies might result in a better understanding of the local team expertise on TAVI utilization. |
doi_str_mv | 10.1017/S0266462319002101 |
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Data from a private healthcare organization in Belo Horizonte, Brazil were used to assess all-cause mortality. Continuous variables were expressed as mean and standard deviation. Cox proportional regression model and Log-Rank test were used to adjust the survival curve.ResultsFifty-two patients were included in the study (mean 83 ± 5.7 years of age, range 67 to 93 years; female 55.8 percent). Patients were characterized by: left ventricular ejection fraction (n = 30; mean 52.9 percent, range 26 to 81 percent); aortic valve area (n = 36; mean 0.68 cm2, range 0.4 to 1.2 cm2); left atrium size (n = 14; range 30 to 61 ml/m2); pulmonary artery pressure (n = 20; mean 53 mmHg, range 31 to 70 mmHg). Death occurred in 19 patients during the follow-up period (mean 8.4 months, range 0 to 60 months). Nine deaths occurred within the first 30 days of follow-up (17.3 percent) and 14 (26.9 percent) in the first year. Stroke occurred in three patients (5.8 percent) in the post-implant period. A pacemaker device was required for nine patients (17.3 percent).ConclusionsTranscatheter aortic valve implantation (TAVI) has become an alternative to surgical aortic valve replacement for patients at high risk for surgery. Real-world studies might result in a better understanding of the local team expertise on TAVI utilization.</description><identifier>ISSN: 0266-4623</identifier><identifier>EISSN: 1471-6348</identifier><identifier>DOI: 10.1017/S0266462319002101</identifier><language>eng</language><publisher>Cambridge: Cambridge University Press</publisher><subject>Aortic stenosis ; Aortic valve ; Atria ; Atrium ; Continuity (mathematics) ; Heart ; Implantation ; Medical prognosis ; Model testing ; Pulmonary arteries ; Pulmonary artery ; Rank tests ; Regression models ; Stenosis ; Surgeons ; Surgery ; Survival ; Transplants & implants ; Ventricle</subject><ispartof>International journal of technology assessment in health care, 2019, Vol.35 (S1), p.47-48</ispartof><rights>Copyright Cambridge University Press 2019</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,4010,27900,27901,27902</link.rule.ids></links><search><creatorcontrib>Soares dos Santos, Augusto Cesar</creatorcontrib><creatorcontrib>Horta, Maria da Glória Cruvinel</creatorcontrib><creatorcontrib>Carvalho, Lélia Maria de Almeida</creatorcontrib><creatorcontrib>Rodrigues, Luíza</creatorcontrib><creatorcontrib>Avelar, Sandra de Oliveira Sapori</creatorcontrib><creatorcontrib>Fernandes, Mariana</creatorcontrib><creatorcontrib>Scherrer, Luciano Rios</creatorcontrib><creatorcontrib>Biscione, Fernando Martin</creatorcontrib><creatorcontrib>Kelles, Silvana Marcia</creatorcontrib><title>PP57 Outcomes On Transcatheter Aortic Valve Implantation</title><title>International journal of technology assessment in health care</title><description>Copyright © Cambridge University Press 20192019Cambridge University PressIntroductionSevere aortic stenosis with symptoms or left ventricular dysfunction has commonly a poor prognosis and therefore, aortic valve replacement is usually performed for patients aiming at improving their functional class and survival rate.MethodsThis retrospective study evaluated a convenience sample of patients at high risk for open surgery for the correction of aortic valve dysfunction treated with TAVI from 2013 to 2018. Data from a private healthcare organization in Belo Horizonte, Brazil were used to assess all-cause mortality. Continuous variables were expressed as mean and standard deviation. Cox proportional regression model and Log-Rank test were used to adjust the survival curve.ResultsFifty-two patients were included in the study (mean 83 ± 5.7 years of age, range 67 to 93 years; female 55.8 percent). Patients were characterized by: left ventricular ejection fraction (n = 30; mean 52.9 percent, range 26 to 81 percent); aortic valve area (n = 36; mean 0.68 cm2, range 0.4 to 1.2 cm2); left atrium size (n = 14; range 30 to 61 ml/m2); pulmonary artery pressure (n = 20; mean 53 mmHg, range 31 to 70 mmHg). Death occurred in 19 patients during the follow-up period (mean 8.4 months, range 0 to 60 months). Nine deaths occurred within the first 30 days of follow-up (17.3 percent) and 14 (26.9 percent) in the first year. Stroke occurred in three patients (5.8 percent) in the post-implant period. A pacemaker device was required for nine patients (17.3 percent).ConclusionsTranscatheter aortic valve implantation (TAVI) has become an alternative to surgical aortic valve replacement for patients at high risk for surgery. Real-world studies might result in a better understanding of the local team expertise on TAVI utilization.</description><subject>Aortic stenosis</subject><subject>Aortic valve</subject><subject>Atria</subject><subject>Atrium</subject><subject>Continuity (mathematics)</subject><subject>Heart</subject><subject>Implantation</subject><subject>Medical prognosis</subject><subject>Model testing</subject><subject>Pulmonary arteries</subject><subject>Pulmonary artery</subject><subject>Rank tests</subject><subject>Regression models</subject><subject>Stenosis</subject><subject>Surgeons</subject><subject>Surgery</subject><subject>Survival</subject><subject>Transplants & 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Transcatheter Aortic Valve Implantation</title><author>Soares dos Santos, Augusto Cesar ; Horta, Maria da Glória Cruvinel ; Carvalho, Lélia Maria de Almeida ; Rodrigues, Luíza ; Avelar, Sandra de Oliveira Sapori ; Fernandes, Mariana ; Scherrer, Luciano Rios ; Biscione, Fernando Martin ; Kelles, Silvana Marcia</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c707-661848d2273f74b9cc91b32db4a6b56047735bfcc830c15635909765c44e828d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Aortic stenosis</topic><topic>Aortic valve</topic><topic>Atria</topic><topic>Atrium</topic><topic>Continuity (mathematics)</topic><topic>Heart</topic><topic>Implantation</topic><topic>Medical prognosis</topic><topic>Model testing</topic><topic>Pulmonary arteries</topic><topic>Pulmonary artery</topic><topic>Rank tests</topic><topic>Regression models</topic><topic>Stenosis</topic><topic>Surgeons</topic><topic>Surgery</topic><topic>Survival</topic><topic>Transplants & implants</topic><topic>Ventricle</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Soares dos Santos, Augusto Cesar</creatorcontrib><creatorcontrib>Horta, Maria da Glória Cruvinel</creatorcontrib><creatorcontrib>Carvalho, Lélia Maria de Almeida</creatorcontrib><creatorcontrib>Rodrigues, Luíza</creatorcontrib><creatorcontrib>Avelar, Sandra de Oliveira Sapori</creatorcontrib><creatorcontrib>Fernandes, Mariana</creatorcontrib><creatorcontrib>Scherrer, Luciano Rios</creatorcontrib><creatorcontrib>Biscione, Fernando Martin</creatorcontrib><creatorcontrib>Kelles, Silvana Marcia</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Immunology Abstracts</collection><collection>Solid State and Superconductivity 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Marcia</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>PP57 Outcomes On Transcatheter Aortic Valve Implantation</atitle><jtitle>International journal of technology assessment in health care</jtitle><date>2019</date><risdate>2019</risdate><volume>35</volume><issue>S1</issue><spage>47</spage><epage>48</epage><pages>47-48</pages><issn>0266-4623</issn><eissn>1471-6348</eissn><abstract>Copyright © Cambridge University Press 20192019Cambridge University PressIntroductionSevere aortic stenosis with symptoms or left ventricular dysfunction has commonly a poor prognosis and therefore, aortic valve replacement is usually performed for patients aiming at improving their functional class and survival rate.MethodsThis retrospective study evaluated a convenience sample of patients at high risk for open surgery for the correction of aortic valve dysfunction treated with TAVI from 2013 to 2018. Data from a private healthcare organization in Belo Horizonte, Brazil were used to assess all-cause mortality. Continuous variables were expressed as mean and standard deviation. Cox proportional regression model and Log-Rank test were used to adjust the survival curve.ResultsFifty-two patients were included in the study (mean 83 ± 5.7 years of age, range 67 to 93 years; female 55.8 percent). Patients were characterized by: left ventricular ejection fraction (n = 30; mean 52.9 percent, range 26 to 81 percent); aortic valve area (n = 36; mean 0.68 cm2, range 0.4 to 1.2 cm2); left atrium size (n = 14; range 30 to 61 ml/m2); pulmonary artery pressure (n = 20; mean 53 mmHg, range 31 to 70 mmHg). Death occurred in 19 patients during the follow-up period (mean 8.4 months, range 0 to 60 months). Nine deaths occurred within the first 30 days of follow-up (17.3 percent) and 14 (26.9 percent) in the first year. Stroke occurred in three patients (5.8 percent) in the post-implant period. A pacemaker device was required for nine patients (17.3 percent).ConclusionsTranscatheter aortic valve implantation (TAVI) has become an alternative to surgical aortic valve replacement for patients at high risk for surgery. Real-world studies might result in a better understanding of the local team expertise on TAVI utilization.</abstract><cop>Cambridge</cop><pub>Cambridge University Press</pub><doi>10.1017/S0266462319002101</doi><tpages>2</tpages></addata></record> |
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subjects | Aortic stenosis Aortic valve Atria Atrium Continuity (mathematics) Heart Implantation Medical prognosis Model testing Pulmonary arteries Pulmonary artery Rank tests Regression models Stenosis Surgeons Surgery Survival Transplants & implants Ventricle |
title | PP57 Outcomes On Transcatheter Aortic Valve Implantation |
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