Dual-Channel Online Optical Detection Platform Integrated with a Visible Light Absorption Approach for Continuous and Simultaneous in Vivo Monitoring of Ascorbic Acid and Copper(II) Ions in a Living Rat Brain

Continuous recording of the dynamic changes of multiple physiologically neurochemicals in vivo is vital to understand the molecular basis of brain functions. For instance, disentangling the complicated interrelationship between ascorbic acid (AA) and copper ions (Cu2+) in signal transduction and hom...

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Veröffentlicht in:	Analytical chemistry (Washington) 2019-12, Vol.91 (24), p.16010-16016
Hauptverfasser:	Wang, Chao, Bi, Xinyu, Wang, Manchao, Zhao, Xu, Lin, Yuqing
Format:	Artikel
Sprache:	eng
Schlagworte:	Ascorbic acid Brain Chemistry Colorimetry Copper Copper compounds Crosstalk Dopamine Electrochemistry Electromagnetic absorption Environmental conditions Homeostasis Hypoxia In vivo methods and tests Internet Ions Linearity Measurement methods Microdialysis Microfluidics Monitoring Nanoparticles Neurodegenerative diseases On-line systems Optics Selectivity Signal transduction Silver Time response
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