A Retrospective Review of the Efficiency of First‐Dose Therapeutic Drug Monitoring of Gentamicin, Amikacin, and Vancomycin in the Pediatric Population

Therapeutic drug monitoring (TDM) has become standard clinical practice for gentamicin, amikacin, and vancomycin to optimize efficacy and reduce toxicity. TDM after the first dose of antibiotic was adopted in our institution. This study aims to evaluate if target therapeutic drug concentrations coul...

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Veröffentlicht in:	Journal of clinical pharmacology 2020-01, Vol.60 (1), p.7-15
Hauptverfasser:	Lim, Wan Xuan Selina, Chua, Wen Bing Brandon, Chua, Jie Min, Lee, Qianyu, Chan, Jer Wei, Sultana, Rehena, Poh, Bao Hui
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Amikacin Amikacin - administration & dosage Amikacin - blood Amikacin - pharmacokinetics Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - blood Anti-Bacterial Agents - pharmacokinetics Antibiotics Child Child, Preschool Cohort Studies Dosage Dose-Response Relationship, Drug Drug dosages Drug Monitoring Female first dose Gentamicin Gentamicins - administration & dosage Gentamicins - blood Gentamicins - pharmacokinetics Hospitals, Pediatric Humans Infant Male Patients pediatrics Retrospective Studies Therapeutic drug monitoring Toxicity Vancomycin Vancomycin - administration & dosage Vancomycin - blood Vancomycin - pharmacokinetics
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