Forecasting Prevalence of HIV-1 Integrase Strand Transfer Inhibitor (INSTI) Drug Resistance: A Modeling Study

Antiretroviral therapy (ART) is a cornerstone of HIV-1 treatment and provides significant health benefits for patients with responsive HIV-1 strains. Integrase strand transfer inhibitors (INSTIs) are the newest class of ART. Although most HIV-1 cases are responsive, a small number are already resist...

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Veröffentlicht in:	Journal of acquired immune deficiency syndromes (1999) 2020-01, Vol.83 (1), p.65-71
Hauptverfasser:	Northrop, Alex J., Pomeroy, Laura W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiretroviral agents Antiretroviral therapy Computer simulation Drug resistance Drug Resistance, Viral - drug effects HIV HIV Integrase - genetics HIV Integrase Inhibitors - pharmacology HIV-1 - drug effects Human immunodeficiency virus Humans Initial conditions Integrase Parameters Public health Stochastic models Stochasticity
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