Mild increases in portal pressure upregulate vascular endothelial growth factor and endothelial nitric oxide synthase in the intestinal microcirculatory bed, leading to a hyperdynamic state

Increased nitric oxide (NO) is the main factor leading to the hyperdynamic circulation associated with advanced portal hypertension (PHT), but the initial mechanisms and the magnitude of increase in portal pressure required to trigger NO production are not known. We addressed these issues by studyin...

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Veröffentlicht in:	American journal of physiology: Gastrointestinal and liver physiology 2006-05, Vol.53 (5), p.G980
Hauptverfasser:	Abraldes, Juan G, Iwakiri, Yasuko, Loureiro-Silva, Mauricio, Haq, Omar
Format:	Artikel
Sprache:	eng
Schlagworte:	Circulatory system Enzymes Hypertension Nitric oxide
Online-Zugang:	Volltext
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