Increased stiffness of the rat liver precedes matrix deposition: implications for fibrosis

Liver fibrosis, the response to chronic liver injury, results from the activation of mesenchymal cells to fibrogenic myofibroblasts. We have recently shown that two key myofibroblast precursor populations, hepatic stellate cells and portal fibroblasts, undergo activation in culture in response to in...

Ausführliche Beschreibung