Inhibition of gastrointestinal lipolysis by Orlistat during digestion of test meals in healthy volunteers

The inhibition of digestive lipases by the antiobesity drug Orlistat along with lipolysis levels and fecal fat excretion were measured in healthy humans. Orlistat was found to be a powerful gastric lipase inhibitor, achieving 46.6-91.4% enzyme inhibition and thus greatly reducing gastric lipolysis o...

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Veröffentlicht in:	American journal of physiology: Gastrointestinal and liver physiology 2001-07, Vol.44 (1), p.G16-G28
Hauptverfasser:	CARRIERE, Frederic, RENOU, Christophe, BEGLINGER, Christoph, HADVARY, Paul, VERGER, Robert, LAUGIER, René, RANSAC, Stéphane, LOPEZ, Veronique, DE CARO, Josiane, FERRATO, Francine, DE CARO, Alain, FLEURY, André, SANWALD-DUCRAY, Patricia, LENGSFELD, Hans
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Clinical trials Drug therapy General and cellular metabolism. Vitamins Medical sciences Obesity Pancreas Pharmacology. Drug treatments Weight control
Online-Zugang:	Volltext
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