Selective Photoredox Trifluoromethylation of Tryptophan‐Containing Peptides

For application in drug discovery and biomedicine, it is crucial to develop new biocompatible methods to modify polypeptides. Herein, a visible‐light‐induced photoredox trifluoromethylation of tryptophan‐containing peptides is reported. Under a mild, biocompatible, and straightforward condition, thi...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	European journal of organic chemistry 2019-12, Vol.2019 (46), p.7596-7605
Hauptverfasser:	Ding, Bo, Weng, Yue, Liu, Yunqing, Song, Chunlan, Yin, Le, Yuan, Jiafan, Ren, Yanrui, Lei, Aiwen, Chiang, Chien‐Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	Biocompatibility Biomolecules Catalytic activity Cross coupling Fluorescence NMR Nuclear magnetic resonance Organic chemistry Peptides Photoredox catalysis Polypeptides Selectivity Synthetic methods Trifluoromethylation Tryptophan
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!