Measuring gluconeogenesis with [2-13C]glycerol and mass isotopomer distribution analysis of glucose

A study concludes that (2-13C)glycerol infusion and mass isotopomer distribution analysis of glucose appear to be useful methods for studies of gluconeogenesis in vitro and in vivo; however, accurate measurements in vivo can be obtained only at the expense of some perturbation of the metabolic pathw...

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Veröffentlicht in:American journal of physiology: endocrinology and metabolism 1995-09, Vol.32 (3), p.E516-E523
Hauptverfasser: PERONI, O, LARGE, V, BEYLOT, M
Format: Artikel
Sprache:eng
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Zusammenfassung:A study concludes that (2-13C)glycerol infusion and mass isotopomer distribution analysis of glucose appear to be useful methods for studies of gluconeogenesis in vitro and in vivo; however, accurate measurements in vivo can be obtained only at the expense of some perturbation of the metabolic pathway studied.
ISSN:0193-1849
1522-1555