Intramyocellular lipid content in type 2 diabetes patients compared with overweight sedentary men and highly trained endurance athletes

Recent evidence suggests that intramyocellular lipid (IMCL) accretion is associated with obesity and the development of insulin resistance and/or type 2 diabetes. However, trained endurance athletes are markedly insulin sensitive, despite an elevated mixed muscle lipid content. In an effort to expla...

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Veröffentlicht in:American journal of physiology: endocrinology and metabolism 2004-09, Vol.50 (3), p.E558-E565
Hauptverfasser: VAN LOON, Luc J. C, KOOPMAN, René, MANDERS, Ralph, VAN DER WEEGEN, Walter, VAN KRANENBURG, Gerrit P, KEIZER, Hans A
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Sprache:eng
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