M2 Macrophages Enhance the Cementoblastic Differentiation of Periodontal Ligament Stem Cells via the Akt and JNK Pathways

Although macrophage (Mφ) polarization has been demonstrated to play crucial roles in cellular osteogenesis across the cascade of events in periodontal regeneration, how polarized Mφ phenotypes influence the cementoblastic differentiation of periodontal ligament stem cells (PDLSCs) remains unknown. I...

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Veröffentlicht in:	Stem cells (Dayton, Ohio) Ohio), 2019-12, Vol.37 (12), p.1567-1580
Hauptverfasser:	Li, Xuan, He, Xiao‐Tao, Kong, De‐Qin, Xu, Xin‐Yue, Wu, Rui‐Xin, Sun, Li‐Juan, Tian, Bei‐Min, Chen, Fa‐Ming
Format:	Artikel
Sprache:	eng
Schlagworte:	Akt pathway AKT protein Alkaline phosphatase Biomedical materials Cell differentiation Cementoblastic differentiation Cementum Chemokines Cyto‐/chemokines Differentiation Gene expression Growth factors Interleukins JNK pathway JNK protein Kinases Leukemia Macrophage polarization Macrophages Modulators Monocytes Osteogenesis Periodontal ligament Phenotypes Regeneration Signal transduction Signaling Stem cells Vascular endothelial growth factor
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