Chronic C75 treatment of diet-induced- obese mice increases fat oxidation and reduces food intake to reduce adipose mass

Obesity and its attendant disorders, such as type 2 diabetes, are global health problems. We previously reported that C75, an inhibitor of fatty acid synthase (FAS) and stimulator of carnitine palmitoyltransferase I (CPT I), caused anorexia and profound weight loss in lean and genetically obese mice...

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Veröffentlicht in:	American journal of physiology: endocrinology and metabolism 2004-07, Vol.50 (1), p.E97-E104
Hauptverfasser:	THUPARI, Jagan N, KIM, Eun-Kyoung, MORAN, Timothy H, RONNETT, Gabriele V, KUHAIDA, Francis P
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Diet Fatty acids Fundamental and applied biological sciences. Psychology Medical sciences Metabolic diseases Obesity Oxidation Peptides Rodents Vertebrates: endocrinology
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