Supraphysiological testosterone enanthate administration prevents bone loss and augments bone strength in gonadectomized male and female rats

1 Geriatric Research, Education and Clinical Center, Veterans Administration Medical Center, Gainesville; and Departments of 2 Applied Physiology and Kinesiology, 3 Orthopedics and Rehabilitation, and 4 Physiological Sciences, University of Florida, Gainesville, Florida Submitted 30 July 2008 ; acce...

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Veröffentlicht in:	American journal of physiology: endocrinology and metabolism 2008-11, Vol.295 (5), p.E1213-E1222
Hauptverfasser:	Yarrow, Joshua F, Conover, Christine F, Purandare, Amol V, Bhakta, Ashish M, Zheng, Naiquan, Conrad, Bryan, Altman, Molly K, Franz, Sarah E, Wronski, Thomas J, Borst, Stephen E
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acids - urine Androgens - administration & dosage Androgens - pharmacology Androgens - therapeutic use Animals Body Weight - drug effects Body Weight - physiology Bone and Bones - drug effects Bone and Bones - metabolism Bones Creatinine - urine Dihydrotestosterone - blood Dihydrotestosterone - metabolism Estradiol - blood Estradiol - metabolism Female Females Femur - drug effects Femur - pathology Hormones Kidney - drug effects Kidney - pathology Male Muscle, Skeletal - drug effects Muscle, Skeletal - pathology Orchiectomy Organ Size - drug effects Osteocalcin - blood Osteoporosis - metabolism Osteoporosis - pathology Osteoporosis - prevention & control Ovariectomy Proteins Rats Rats, Inbred F344 Rodents Studies Tensile Strength - drug effects Testosterone - administration & dosage Testosterone - analogs & derivatives Testosterone - blood Testosterone - metabolism Testosterone - pharmacology Testosterone - therapeutic use Tibia - drug effects Tibia - metabolism
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