Increased leptin, decreased adiponectin and FGF21 concentrations in adolescent offspring of women with gestational diabetes

Objective Fetal exposure to gestational diabetes mellitus (GDM) increases the risk of metabolic diseases in the offspring. Leptin, adiponectin, and fibroblast growth factor 21 (FGF21) may play potential roles in the underlying disease mechanisms. We investigated the impact of fetal exposure to GDM o...

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Veröffentlicht in:	European journal of endocrinology 2019-12, Vol.181 (6), p.691-700
Hauptverfasser:	Kampmann, Freja B, Thuesen, Anne Cathrine B, Hjort, Line, Bjerregaard, Anne A, Chavarro, Jorge E, Frystyk, Jan, Bjerre, Mette, Tetens, Inge, Olsen, Sjurdur F, Vaag, Allan A, Damm, Peter, Grunnet, Louise G
Format:	Artikel
Sprache:	eng
Schlagworte:	Adiponectin Adiponectin - blood Adipose tissue Adolescent Adolescents Birth Weight - physiology Body Mass Index Breast Feeding Child Children Clinical Study Diabetes Diabetes mellitus Diabetes, Gestational - blood Dual energy X-ray absorptiometry Female Fetuses Fibroblast growth factors Fibroblast Growth Factors - blood Humans Immunoassay Insulin Leptin Leptin - blood Maternal Inheritance - physiology Metabolic disorders Metabolism Offspring Pregnancy Puberty
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