Synthesis of Functionalized Tetrahydropyridines by SnCl4‐Mediated Cycloaddition between Donor–AcceptorCyclobutanes and Nitriles

Cycloadditions of strained carbocycles promoted by Lewis acids are powerful methods to construct heterocyclic frameworks. In fact, the formal [3+2] cycloadditions of donor–acceptor (DA) cyclopropanes with nitriles has seen particular success in synthesis. In this work, we report on the first [4+2] c...

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Veröffentlicht in:	Chemistry : a European journal 2019-12, Vol.25 (67), p.15244-15247
Hauptverfasser:	Tong, David, Wu, Jackie, Bazinski, Nathan, Koo, Donghyun, Vemula, Naresh, Pagenkopf, Brian L
Format:	Artikel
Sprache:	eng
Schlagworte:	Aliphatic compounds Aromatic compounds Chemistry Cyanides Cycloaddition Cyclobutane Diesters Lewis acid Nitriles Organic compounds Synthesis Tetrahydropyridines
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