Comparison of the Early Effects of Brimonidine and Apraclonidine as Topical Ocular Hypotensive Agents

OBJECTIVE To compare the mechanism of action of short-term administration of brimonidine tartrate and apraclonidine hydrochloride as topical ocular hypotensive agents. SUBJECTS AND METHODS Two randomized, double-masked, placebo-controlled studies of 19 normal human subjects were carried out. The fir...

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Veröffentlicht in:	Archives of ophthalmology (1960) 1999-05, Vol.117 (5), p.586-591
Hauptverfasser:	Maus, Todd L, Nau, Cherie, Brubaker, Richard F
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Topical Adrenergic alpha-Agonists - administration & dosage Adrenergic alpha-Agonists - pharmacology Antihypertensive Agents - administration & dosage Antihypertensive Agents - pharmacology Aqueous Humor - metabolism Biological and medical sciences Brimonidine Tartrate Clonidine - administration & dosage Clonidine - analogs & derivatives Clonidine - pharmacology Double-Blind Method Drug Synergism Drug Therapy, Combination Eye Fluorophotometry Humans Intraocular Pressure - drug effects Latanoprost Medical sciences Ophthalmic Solutions - administration & dosage Ophthalmic Solutions - pharmacology Pharmacology. Drug treatments Prostaglandins F, Synthetic - administration & dosage Prostaglandins F, Synthetic - pharmacology Quinoxalines - administration & dosage Quinoxalines - pharmacology Timolol - administration & dosage Timolol - pharmacology
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