Cocoa antioxidants and cardiovascular health
An increasing body of epidemiologic evidence supports the concept that diets rich in fruits and vegetables can promote health and attenuate, or delay, the onset of various diseases. Epidemiologic data support the idea that these health benefits are causally linked to the consumption of certain flavo...
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| Veröffentlicht in: | The American journal of clinical nutrition 2005, Vol.81 (1), p.298S-303S |
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| container_title | The American journal of clinical nutrition |
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| creator | Keen, Carl L Holt, Roberta R Oteiza, Patricia I Fraga, Cesar G Schmitz, Harold H |
| description | An increasing body of epidemiologic evidence supports the concept that diets rich in fruits and vegetables can promote health and attenuate, or delay, the onset of various diseases. Epidemiologic data support the idea that these health benefits are causally linked to the consumption of certain flavonoids present in fruit and vegetables. In the context of cardiovascular health, a particular group of flavonoids, namely, the flavan-3-ols (flavanols), has received attention. Flavanol-rich, plant-derived foods and beverages include wine, tea, and various fruits and berries, as well as cocoa and cocoa products. Numerous dietary intervention studies in humans and animals indicate that flavanol-rich foods and beverages might exert cardioprotective effects with respect to vascular function and platelet reactivity. This review discusses the bioactivity of flavanols in the context of cardiovascular health, with respect to their bioavailability, their antioxidant properties, and their vascular effects. |
| doi_str_mv | 10.1093/ajcn/81.1.298s |
| format | Article |
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Epidemiologic data support the idea that these health benefits are causally linked to the consumption of certain flavonoids present in fruit and vegetables. In the context of cardiovascular health, a particular group of flavonoids, namely, the flavan-3-ols (flavanols), has received attention. Flavanol-rich, plant-derived foods and beverages include wine, tea, and various fruits and berries, as well as cocoa and cocoa products. Numerous dietary intervention studies in humans and animals indicate that flavanol-rich foods and beverages might exert cardioprotective effects with respect to vascular function and platelet reactivity. This review discusses the bioactivity of flavanols in the context of cardiovascular health, with respect to their bioavailability, their antioxidant properties, and their vascular effects.</description><identifier>ISSN: 0002-9165</identifier><identifier>EISSN: 1938-3207</identifier><identifier>DOI: 10.1093/ajcn/81.1.298s</identifier><identifier>PMID: 15640494</identifier><identifier>CODEN: AJCNAC</identifier><language>eng</language><publisher>Bethesda, MD: American Society for Clinical Nutrition</publisher><subject>Animals ; antioxidant activity ; Antioxidants ; Antioxidants - pharmacokinetics ; Antioxidants - therapeutic use ; Bioavailability ; Biological and medical sciences ; Biological Availability ; Blood Platelets - drug effects ; Cacao ; cardioprotective effect ; Cardiovascular Diseases - etiology ; Cardiovascular Diseases - prevention & control ; Circulatory system ; Cocoa ; cocoa products ; diet ; Endothelium, Vascular - drug effects ; Endothelium, Vascular - physiology ; Feeding. Feeding behavior ; flavanols ; Flavonoids - pharmacokinetics ; Flavonoids - therapeutic use ; Fruit ; fruits ; Fundamental and applied biological sciences. Psychology ; Health ; Homeostasis - drug effects ; Humans ; nutritional intervention ; plant-based foods ; Proanthocyanidins - pharmacokinetics ; Proanthocyanidins - therapeutic use ; Rats ; small fruits ; tea ; Vegetables ; Vertebrates: anatomy and physiology, studies on body, several organs or systems ; wines</subject><ispartof>The American journal of clinical nutrition, 2005, Vol.81 (1), p.298S-303S</ispartof><rights>2005 INIST-CNRS</rights><rights>Copyright American Society for Clinical Nutrition, Inc. 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Epidemiologic data support the idea that these health benefits are causally linked to the consumption of certain flavonoids present in fruit and vegetables. In the context of cardiovascular health, a particular group of flavonoids, namely, the flavan-3-ols (flavanols), has received attention. Flavanol-rich, plant-derived foods and beverages include wine, tea, and various fruits and berries, as well as cocoa and cocoa products. Numerous dietary intervention studies in humans and animals indicate that flavanol-rich foods and beverages might exert cardioprotective effects with respect to vascular function and platelet reactivity. This review discusses the bioactivity of flavanols in the context of cardiovascular health, with respect to their bioavailability, their antioxidant properties, and their vascular effects.</description><subject>Animals</subject><subject>antioxidant activity</subject><subject>Antioxidants</subject><subject>Antioxidants - pharmacokinetics</subject><subject>Antioxidants - therapeutic use</subject><subject>Bioavailability</subject><subject>Biological and medical sciences</subject><subject>Biological Availability</subject><subject>Blood Platelets - drug effects</subject><subject>Cacao</subject><subject>cardioprotective effect</subject><subject>Cardiovascular Diseases - etiology</subject><subject>Cardiovascular Diseases - prevention & control</subject><subject>Circulatory system</subject><subject>Cocoa</subject><subject>cocoa products</subject><subject>diet</subject><subject>Endothelium, Vascular - drug effects</subject><subject>Endothelium, Vascular - physiology</subject><subject>Feeding. Feeding behavior</subject><subject>flavanols</subject><subject>Flavonoids - pharmacokinetics</subject><subject>Flavonoids - therapeutic use</subject><subject>Fruit</subject><subject>fruits</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Health</subject><subject>Homeostasis - drug effects</subject><subject>Humans</subject><subject>nutritional intervention</subject><subject>plant-based foods</subject><subject>Proanthocyanidins - pharmacokinetics</subject><subject>Proanthocyanidins - therapeutic use</subject><subject>Rats</subject><subject>small fruits</subject><subject>tea</subject><subject>Vegetables</subject><subject>Vertebrates: anatomy and physiology, studies on body, several organs or systems</subject><subject>wines</subject><issn>0002-9165</issn><issn>1938-3207</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkE1LAzEQhoMotlavHrUI3txtJl-bHKX4BQUPtecwu5vYLW23Jl3Rf29KFzwNA8_7DvMQcg00B2r4BFfVdqIhh5wZHU_IEAzXGWe0OCVDSinLDCg5IBcxrigFJrQ6JwOQSlBhxJA8TNuqxTFu903709RpxrTU4wpD3bTfGKtujWG8dLjeLy_Jmcd1dFf9HJHF89PH9DWbvb-8TR9nWSU03WfeC0MZd4AMhSkLKkXJuROMCelQeVkaXyrNDGrmjayMBFmolGKK1056PiJ3x95daL86F_d21XZhm05axsFIxZhJUH6EqtDGGJy3u9BsMPxaoPbgxh7cWA0WbHIzT4GbvrUrN67-x3sZCbjvgfQ2rn3AbdXEf04JYVgBibs9ch5bi58hMYs5o6CS70JpA_wPfgB0og</recordid><startdate>2005</startdate><enddate>2005</enddate><creator>Keen, Carl L</creator><creator>Holt, Roberta R</creator><creator>Oteiza, Patricia I</creator><creator>Fraga, Cesar G</creator><creator>Schmitz, Harold H</creator><general>American Society for Clinical Nutrition</general><general>American Society for Clinical Nutrition, Inc</general><scope>FBQ</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>7T7</scope><scope>7TS</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>P64</scope></search><sort><creationdate>2005</creationdate><title>Cocoa antioxidants and cardiovascular health</title><author>Keen, Carl L ; Holt, Roberta R ; Oteiza, Patricia I ; Fraga, Cesar G ; Schmitz, Harold H</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c480t-ff49023e1a2a49b7054b33e42245ea6f5b9fb6829a82f95c951576ff4263de5f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Animals</topic><topic>antioxidant activity</topic><topic>Antioxidants</topic><topic>Antioxidants - pharmacokinetics</topic><topic>Antioxidants - therapeutic use</topic><topic>Bioavailability</topic><topic>Biological and medical sciences</topic><topic>Biological Availability</topic><topic>Blood Platelets - drug effects</topic><topic>Cacao</topic><topic>cardioprotective effect</topic><topic>Cardiovascular Diseases - etiology</topic><topic>Cardiovascular Diseases - prevention & control</topic><topic>Circulatory system</topic><topic>Cocoa</topic><topic>cocoa products</topic><topic>diet</topic><topic>Endothelium, Vascular - drug effects</topic><topic>Endothelium, Vascular - physiology</topic><topic>Feeding. Feeding behavior</topic><topic>flavanols</topic><topic>Flavonoids - pharmacokinetics</topic><topic>Flavonoids - therapeutic use</topic><topic>Fruit</topic><topic>fruits</topic><topic>Fundamental and applied biological sciences. 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| subjects | Animals antioxidant activity Antioxidants Antioxidants - pharmacokinetics Antioxidants - therapeutic use Bioavailability Biological and medical sciences Biological Availability Blood Platelets - drug effects Cacao cardioprotective effect Cardiovascular Diseases - etiology Cardiovascular Diseases - prevention & control Circulatory system Cocoa cocoa products diet Endothelium, Vascular - drug effects Endothelium, Vascular - physiology Feeding. Feeding behavior flavanols Flavonoids - pharmacokinetics Flavonoids - therapeutic use Fruit fruits Fundamental and applied biological sciences. Psychology Health Homeostasis - drug effects Humans nutritional intervention plant-based foods Proanthocyanidins - pharmacokinetics Proanthocyanidins - therapeutic use Rats small fruits tea Vegetables Vertebrates: anatomy and physiology, studies on body, several organs or systems wines |
| title | Cocoa antioxidants and cardiovascular health |
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