Strabismus in Premature Infants in the First Year of Life

OBJECTIVES To present the 3- and 12-month strabismus data from 3030 premature infants with birth weights less than 1251 g enrolled in the Multicenter Trial of Cryotherapy for Retinopathy of Prematurity. DESIGN Data from the 3- and 12-month examinations conducted at 23 regional study centers were tab...

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Veröffentlicht in:Archives of ophthalmology (1960) 1998-03, Vol.116 (3), p.329-333
Hauptverfasser: Bremer, Don L, Palmer, Earl A, Fellows, Rae R, Baker, John D, Hardy, Robert J, Tung, Betty, Rogers, Gary L
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container_end_page 333
container_issue 3
container_start_page 329
container_title Archives of ophthalmology (1960)
container_volume 116
creator Bremer, Don L
Palmer, Earl A
Fellows, Rae R
Baker, John D
Hardy, Robert J
Tung, Betty
Rogers, Gary L
description OBJECTIVES To present the 3- and 12-month strabismus data from 3030 premature infants with birth weights less than 1251 g enrolled in the Multicenter Trial of Cryotherapy for Retinopathy of Prematurity. DESIGN Data from the 3- and 12-month examinations conducted at 23 regional study centers were tabulated for all infants. The main outcome measure, ocular motility, was compared with baseline demographic variables and retinopathy of prematurity severity for the worse eye. Findings at 3 months were compared with the incidence of strabismus at 12 months. RESULTS At 3 months, 200 (6.6%) of the 3030 infants were strabismic. In the 2449 infants examined at both time points, 289 (11.8%) were found to have strabismus at 12 months. Retinopathy of prematurity was significant for strabismus at both 3 and 12 months (P
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DESIGN Data from the 3- and 12-month examinations conducted at 23 regional study centers were tabulated for all infants. The main outcome measure, ocular motility, was compared with baseline demographic variables and retinopathy of prematurity severity for the worse eye. Findings at 3 months were compared with the incidence of strabismus at 12 months. RESULTS At 3 months, 200 (6.6%) of the 3030 infants were strabismic. In the 2449 infants examined at both time points, 289 (11.8%) were found to have strabismus at 12 months. Retinopathy of prematurity was significant for strabismus at both 3 and 12 months (P&lt;.001). The presence of strabismus at 3 months was found to be a highly significant predictor of strabismus at 12 months. Anisometropia, abnormal fixation, and unfavorable retinal structure also were significant predictors of strabismus at 1 year. The total prevalence of strabismus in the first year of life was 14.7%. CONCLUSION The presence of acute-phase retinopathy of prematurity places the premature infant at increased risk for strabismus.Arch Ophthalmol. 1998;116:329-333--&gt;</description><identifier>ISSN: 0003-9950</identifier><identifier>ISSN: 2168-6165</identifier><identifier>EISSN: 1538-3601</identifier><identifier>EISSN: 2168-6173</identifier><identifier>DOI: 10.1001/archopht.116.3.329</identifier><language>eng</language><publisher>Chicago, IL: American Medical Association</publisher><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Biological and medical sciences ; Emergency and intensive care: neonates and children. Prematurity. Sudden death ; Intensive care medicine ; Medical sciences</subject><ispartof>Archives of ophthalmology (1960), 1998-03, Vol.116 (3), p.329-333</ispartof><rights>1998 INIST-CNRS</rights><rights>Copyright American Medical Association Mar 1998</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a385t-c9fdd9b1774ab77be15c3ee2b567a89c25c6e65da2d86e340d78d2a485cd4d913</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=2179639$$DView record in Pascal Francis$$Hfree_for_read</backlink></links><search><creatorcontrib>Bremer, Don L</creatorcontrib><creatorcontrib>Palmer, Earl A</creatorcontrib><creatorcontrib>Fellows, Rae R</creatorcontrib><creatorcontrib>Baker, John D</creatorcontrib><creatorcontrib>Hardy, Robert J</creatorcontrib><creatorcontrib>Tung, Betty</creatorcontrib><creatorcontrib>Rogers, Gary L</creatorcontrib><title>Strabismus in Premature Infants in the First Year of Life</title><title>Archives of ophthalmology (1960)</title><description>OBJECTIVES To present the 3- and 12-month strabismus data from 3030 premature infants with birth weights less than 1251 g enrolled in the Multicenter Trial of Cryotherapy for Retinopathy of Prematurity. DESIGN Data from the 3- and 12-month examinations conducted at 23 regional study centers were tabulated for all infants. The main outcome measure, ocular motility, was compared with baseline demographic variables and retinopathy of prematurity severity for the worse eye. Findings at 3 months were compared with the incidence of strabismus at 12 months. RESULTS At 3 months, 200 (6.6%) of the 3030 infants were strabismic. In the 2449 infants examined at both time points, 289 (11.8%) were found to have strabismus at 12 months. Retinopathy of prematurity was significant for strabismus at both 3 and 12 months (P&lt;.001). The presence of strabismus at 3 months was found to be a highly significant predictor of strabismus at 12 months. Anisometropia, abnormal fixation, and unfavorable retinal structure also were significant predictors of strabismus at 1 year. The total prevalence of strabismus in the first year of life was 14.7%. CONCLUSION The presence of acute-phase retinopathy of prematurity places the premature infant at increased risk for strabismus.Arch Ophthalmol. 1998;116:329-333--&gt;</description><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Biological and medical sciences</subject><subject>Emergency and intensive care: neonates and children. Prematurity. 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Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Biological and medical sciences</topic><topic>Emergency and intensive care: neonates and children. Prematurity. Sudden death</topic><topic>Intensive care medicine</topic><topic>Medical sciences</topic><toplevel>online_resources</toplevel><creatorcontrib>Bremer, Don L</creatorcontrib><creatorcontrib>Palmer, Earl A</creatorcontrib><creatorcontrib>Fellows, Rae R</creatorcontrib><creatorcontrib>Baker, John D</creatorcontrib><creatorcontrib>Hardy, Robert J</creatorcontrib><creatorcontrib>Tung, Betty</creatorcontrib><creatorcontrib>Rogers, Gary L</creatorcontrib><collection>Pascal-Francis</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Premium</collection><jtitle>Archives of ophthalmology (1960)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bremer, Don L</au><au>Palmer, Earl A</au><au>Fellows, Rae R</au><au>Baker, John D</au><au>Hardy, Robert J</au><au>Tung, Betty</au><au>Rogers, Gary L</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Strabismus in Premature Infants in the First Year of Life</atitle><jtitle>Archives of ophthalmology (1960)</jtitle><date>1998-03-01</date><risdate>1998</risdate><volume>116</volume><issue>3</issue><spage>329</spage><epage>333</epage><pages>329-333</pages><issn>0003-9950</issn><issn>2168-6165</issn><eissn>1538-3601</eissn><eissn>2168-6173</eissn><abstract>OBJECTIVES To present the 3- and 12-month strabismus data from 3030 premature infants with birth weights less than 1251 g enrolled in the Multicenter Trial of Cryotherapy for Retinopathy of Prematurity. DESIGN Data from the 3- and 12-month examinations conducted at 23 regional study centers were tabulated for all infants. The main outcome measure, ocular motility, was compared with baseline demographic variables and retinopathy of prematurity severity for the worse eye. Findings at 3 months were compared with the incidence of strabismus at 12 months. RESULTS At 3 months, 200 (6.6%) of the 3030 infants were strabismic. In the 2449 infants examined at both time points, 289 (11.8%) were found to have strabismus at 12 months. Retinopathy of prematurity was significant for strabismus at both 3 and 12 months (P&lt;.001). The presence of strabismus at 3 months was found to be a highly significant predictor of strabismus at 12 months. Anisometropia, abnormal fixation, and unfavorable retinal structure also were significant predictors of strabismus at 1 year. The total prevalence of strabismus in the first year of life was 14.7%. CONCLUSION The presence of acute-phase retinopathy of prematurity places the premature infant at increased risk for strabismus.Arch Ophthalmol. 1998;116:329-333--&gt;</abstract><cop>Chicago, IL</cop><pub>American Medical Association</pub><doi>10.1001/archopht.116.3.329</doi><tpages>5</tpages></addata></record>
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subjects Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Emergency and intensive care: neonates and children. Prematurity. Sudden death
Intensive care medicine
Medical sciences
title Strabismus in Premature Infants in the First Year of Life
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