When encephalitogenic T cells collaborate with microglia in multiple sclerosis

Immune cells mediate critical inflammatory and neurodegenerative processes in the CNS in individuals with multiple sclerosis (MS). In MS, activated microglia, border-associated macrophages and monocyte-derived macrophages in the CNS can encounter T cells that have infiltrated the brain parenchyma fr...

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Veröffentlicht in:	Nature reviews. Neurology 2019-12, Vol.15 (12), p.704-717
Hauptverfasser:	Dong, Yifei, Yong, V. Wee
Format:	Artikel
Sprache:	eng
Schlagworte:	692/308/575 692/698/1543/1565/1597/554 692/698/1543/1565/342/1952 692/699/375/1411/1666 Animals Care and treatment Cell Communication - physiology Development and progression Encephalomyelitis Encephalomyelitis, Autoimmune, Experimental - immunology Encephalomyelitis, Autoimmune, Experimental - metabolism Health aspects Homeostasis Homeostasis - physiology Humans Lymphocytes Medicine Medicine & Public Health Microglia - immunology Microglia - metabolism Multiple sclerosis Multiple Sclerosis - immunology Multiple Sclerosis - metabolism Neurology Physiological aspects Review Article T cells T-Lymphocytes - immunology T-Lymphocytes - metabolism
Online-Zugang:	Volltext
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