Soluble Guanylyl Cyclase Alpha1 Subunit: A New Marker for Estrogenicity of Endocrine Disruptor Compounds

Endocrine‐disrupting chemicals (EDCs) include widespread naturally occurring and synthetic substances in the environment that adversely affect humans and wildlife. Because of the increasing numbers of EDCs, screening methods and ideal biomarkers to determine EDC potencies at relevant environmental c...

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Veröffentlicht in:	Environmental toxicology and chemistry 2019-12, Vol.38 (12), p.2719-2728
Hauptverfasser:	Pino, María Teresa L., Ronchetti, Sonia A., Cordeiro, Georgina, Bollani, Sabrina, Duvilanski, Beatriz H., Cabilla, Jimena P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Benzhydryl Compounds - toxicity Biomarkers Biotechnology Cell Line, Tumor Disruption Endocrine disruptors Endocrine Disruptors - toxicity Endocrine‐disrupting compounds Estradiol - pharmacology Estrogen receptors Estrogenic activity Estrogenic compounds Estrogens Female Fulvestrant - pharmacology Guanylate cyclase Heavy metals Humans Hydrocarbons, Chlorinated - toxicity Marker of exposure Metals, Heavy - toxicity Organic chemistry Pesticides Phenols - toxicity Pituitary Protein Binding Proteins Receptors, Estrogen - antagonists & inhibitors Receptors, Estrogen - metabolism Screening Signal Transduction - drug effects Soluble Guanylyl Cyclase - metabolism Soluble guanylyl cyclase alpha1 subunit Tumor cell lines Up-Regulation - drug effects Wildlife Xenoestrogens
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