Prevalence of anti-basal ganglia antibodies in adultobsessive–compulsive disorder: cross-sectional study

BackgroundSymptoms of obsessive–compulsive disorder (OCD) have been described in neuropsychiatric syndromes associated with streptococcal infections. It is proposed that antibodies raised against streptococcal proteinscross-react with neuronal proteins (antigens) in the brain, particularly in the ba...

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Veröffentlicht in:	British journal of psychiatry 2012-05, Vol.200 (5), p.381-386
Hauptverfasser:	Nicholson Timothy R J, Sumudu, Ferdinando, Krishnaiah, Ravikumar B, Anhoury Sophie, Lennox, Belinda R, Mataix-Cols, David, Cleare, Anthony, Veale, David M, Drummond, Lynne M, Fineberg, Naomi A, Church, Andrew J, Giovannoni Gavin, Heyman Isobel
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antigens Autoimmunity Basal ganglia Brain Clinical variables Comorbidity Cross-sectional studies Hospitals Immunoglobulins Infections Neurosciences Neuroses Obsessive compulsive disorder Pathogenesis Phlebotomy Phosphopyruvate hydratase Proteins Psychiatry Pyruvate kinase Pyruvic acid Rheumatic fever Risk factors Schizophrenia Streptococcus infections Tourette syndrome Western blotting Zebrin II
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